PTGS1
PTGS1，即前列腺素内过氧化物合酶1，别名COX1、PGHS1、PHS1等。这是一种在人体中的酶，主要在9号染色体上表达。PTGS1的作用机制是通过催化花生四烯酸合成前列腺素H2（PGH2），这是所有前列腺素和血栓素的前体。前列腺素是一类具有多种生理作用的生物活性物质，包括调节炎症反应、疼痛感知、发热以及血小板聚集等。PTGS1对于维持正常生理功能至关重要，但其异常表达也与多种疾病相关，尤其是与炎症和肿瘤发生发展有关。例如，PTGS1的高表达与肿瘤细胞的增殖和抗凋亡能力增强相关，因此它也是许多非甾体抗炎药和抗癌药物的作用靶点。
热销产品
PTGS1 Recombinant Monoclonal Antibody (CSB-RA918236A0HU)
验证数据
Western Blot
Positive WB detected in: HL60 whole cell lysate, SH-SY5Y whole cell lysate, Mouse liver tissue
All lanes: PTGS1 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 69, 65, 62, 57, 72, 73 kDa
Observed band size: 72 kDa
Overlay histogram showing Hela cells stained with CSB-RA918236A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1µg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1µg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.
PTGS1 Antibodies
PTGS1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA164506 | PTGS1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA000360 | PTGS1 Antibody | Human | WB |
| CSB-PA001761 | PTGS1 Antibody | Human | WB, IHC, ELISA |
| CSB-PA035390 | PTGS1 Antibody | Human | ELISA,IHC |
| CSB-RA918236A0HU | PTGS1 Recombinant Monoclonal Antibody | Human, Mouse | ELISA, WB, FC |
PTGS1 Proteins
PTGS1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP018985HU CSB-BP018985HU CSB-MP018985HU CSB-EP018985HU-B |
Recombinant Human Prostaglandin G/H synthase 1 (PTGS1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP018985HU | Recombinant Human Prostaglandin G/H synthase 1 (PTGS1) | E.coli |
| CSB-EP018985HUa0 | Recombinant Human Prostaglandin G/H synthase 1 (PTGS1) | E.coli |
