PRNP
PRNP，即朊蛋白前体，别名AltPrP、ASCR、CD230。它是一种由PRNP基因编码的蛋白质，广泛存在于人体多种组织中，尤其在中枢神经系统。PRNP的作用机制涉及其正常形式PrPC参与细胞黏附和信号传导，而当PrPC错误折叠成PrPSc时，会形成淀粉样纤维并积累，引发神经细胞损伤。PRNP的生物学意义在于其与多种神经退行性疾病密切相关，尤其是朊病毒病，如克雅氏病等，这些疾病由PrPSc的异常聚集导致，目前尚缺乏有效治疗手段，使PRNP成为神经科学研究的重要靶点。
热销产品
PRNP Antibody (CSB-PA018739LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA018739LA01HU at dilution of 1:100
Immunofluorescent analysis of PC-3 cells using CSB-PA018739LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Human Major prion protein(PRNP) ELISA kit (CSB-EL018739HU)
验证数据
货号：CSB-EL018739HU
规格：96T/48T
灵敏度：0.078 ng/mL
检测范围：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
PRNP Antibodies
PRNP for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA018739GA01HU | PRNP Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA018739LA01HU | PRNP Antibody | Human | ELISA, IHC, IF |
| CSB-PA018739LB01HU | PRNP Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018739LC01HU | PRNP Antibody, FITC conjugated | Human | |
| CSB-PA018739LD01HU | PRNP Antibody, Biotin conjugated | Human | ELISA |
PRNP ELISA Kit
PRNP ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL018739HU | Human Major prion protein(PRNP) ELISA kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
