PRMT3
PRMT3，即蛋白质精氨酸甲基转移酶3，别名ProteinArginineMethyltransferase3。它是一种由人类基因组编码的酶，属于蛋白质精氨酸甲基转移酶家族成员之一。PRMT3的作用机制主要是催化甲基基团从S-腺苷甲硫氨酸(SAM)转移到蛋白质精氨酸残基上，形成单甲基化(MMA)和非对称二甲基化(ADMA)修饰。这种甲基化修饰能够调控多种蛋白质的功能，包括转录因子、核糖体蛋白和信号转导分子。PRMT3参与调控细胞生长、增殖、分化和基因表达等重要生物学过程。异常的PRMT3表达或活性与肿瘤、二型糖尿病等疾病的发生发展密切相关。PRMT3通过精氨酸甲基化修饰相应的底物控制着许多重要的细胞生物学过程。
热销产品
PRMT3 Antibody (CSB-PA018733LA01HU)
验证数据
Western blot
All lanes: PRMT3 antibody at 7μg/ml + MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 60, 53 kDa
Observed band size: 53 kDa
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018733LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA018733LA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA018733LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
PRMT3 Antibodies
PRMT3 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA018733GA01HU | PRMT3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA948631 | PRMT3 Antibody | Human | ELISA,IHC |
| CSB-PA018733LA01HU | PRMT3 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA018733LB01HU | PRMT3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018733LC01HU | PRMT3 Antibody, FITC conjugated | Human | |
| CSB-PA018733LD01HU | PRMT3 Antibody, Biotin conjugated | Human | ELISA |
PRMT3 Proteins
PRMT3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP018733HU CSB-EP018733HU CSB-BP018733HU CSB-MP018733HU CSB-EP018733HU-B |
Recombinant Human Protein arginine N-methyltransferase 3 (PRMT3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
