PIK3R3
PIK3R3，即磷酸肌醇3激酶调节亚基3，别名p55、p55PIK。PIK3R3是磷脂酰肌醇3激酶（PI3K）的一个调节亚基，包含两个SH2结构域，通过这些结构域，它能够结合激活的蛋白酪氨酸激酶以调节其活性。PIK3R3与PI3K的催化亚基结合，通过iSH2域与p110催化亚基相互作用，参与细胞内信号传导，特别是在生长因子信号通路中。PIK3R3在细胞增殖、肿瘤生长、炎症反应以及脂质代谢中扮演重要角色。PIK3R3的异常表达与多种癌症的发生发展相关，包括卵巢癌，并且可能参与调节癌症干细胞的特性和功能，影响肿瘤的进展和化疗抗性。
热销产品
PIK3R3 Antibody (CSB-PA852884ESR2HU)
验证数据
Western blot
All lanes: PIK3R3 antibody at 3.5μg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: Mouse gonadal tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 55, 48, 44 kDa
Observed band size: 55 kDa
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA852884ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA852884ESR2HU at dilution of 1:100
PIK3R3 Antibodies
PIK3R3 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA018006GA01HU | PIK3R3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA622420 | PIK3R3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA159945 | PIK3R3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA852884ESR1HU | PIK3R3 Antibody | Human | ELISA, IHC |
| CSB-PA852884ESR2HU | PIK3R3 Antibody | Human, Mouse | ELISA, WB, IHC |
PIK3R3 Proteins
PIK3R3 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP018006BO CSB-EP018006BO CSB-BP018006BO CSB-MP018006BO CSB-EP018006BO-B |
Recombinant Bovine Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3R3 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP727043MO CSB-EP727043MO CSB-BP727043MO CSB-MP727043MO CSB-EP727043MO-B |
Recombinant Mouse Phosphatidylinositol 3-kinase regulatory subunit gamma (Pik3r3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3R3 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP733971RA CSB-EP733971RA CSB-BP733971RA CSB-MP733971RA CSB-EP733971RA-B |
Recombinant Rat Phosphatidylinositol 3-kinase regulatory subunit gamma (Pik3r3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3R3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP852884HU CSB-EP852884HU CSB-BP852884HU CSB-MP852884HU CSB-EP852884HU-B |
Recombinant Human Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
