PEX19
PEX19，即过氧化物酶体生物发生因子19，别名PXF、HK33、PMP1、PMPI、PXMP1、PBD12A、D1S2223E。它在人类中位于1q23.2染色体上，编码的蛋白质是早期过氧化物酶体生物发生所必需的。PEX19的作用机制包括与Pex3的相互作用以及与含膜过氧化物酶体靶向信号（mPTS）的PMPs的相互作用。PEX19的N末端和C末端构建体分别负责与Pex3和PMPs的结合。Pex25对于过氧化物酶体与CTC变体的形成至关重要，其过表达增强了它们与Pex3的相互作用，并有助于NTC和CTC Pex19变体的生长。PEX19基因的缺陷可能导致Zellweger综合征（ZWS）以及过氧化物酶体生物发生障碍互补组14（PBD-CG14），显示了其在人类健康中的重要性。
热销产品
Recombinant Human Peroxisomal biogenesis factor 19 (PEX19) (Active) (CSB-EP017802HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized ABCD1 at 5 μg/ml can bind human PEX19, the EC50 of human PEX19 is 22.96-33.00 μg/ml.
PEX19 Antibody (CSB-PA017802DSR2HU)
验证数据
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA017802DSR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA017802DSR2HU at dilution of 1:100
PEX19 Antibodies
PEX19 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA017802GA01HU | PEX19 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA040121 | PEX19 Antibody | Human | WB, IHC, ELISA |
| CSB-PA017802DSR2HU | PEX19 Antibody | Human | ELISA, IHC |
PEX19 Proteins
PEX19 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP017802HU CSB-BP017802HU CSB-MP017802HU CSB-EP017802HU-B |
Recombinant Human Peroxisomal biogenesis factor 19 (PEX19) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP017802HU | Recombinant Human Peroxisomal biogenesis factor 19 (PEX19) (Active) | E.coli |
