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PDGFD

PDGFD,即血小板衍生生长因子D,别名PDGF-D、PCDGF-B等。它是一种由PDGFD基因编码的细胞因子,属于血小板衍生生长因子家族成员。PDGFD在多种细胞类型中表达,尤其在血管生成、组织修复和免疫反应中发挥作用。PDGFD的作用机制涉及与其特异性受体PDGFR-β结合,激活下游的信号传导途径,如PI3K/AKT、RAS/RAF/MEK/ERK等。PDGFD参与了多种生理和病理过程的调控,包括细胞增殖、迁移、分化和血管新生。PDGFD的功能异常与多种疾病有关,如动脉粥样硬化、肿瘤血管生成、炎症性肠病等,是心血管疾病、肿瘤和炎症性疾病研究和治疗中的一个潜在靶点。

热销产品

PDGFD Antibody (CSB-PA887935ESR2HU)

验证数据

CSB-PA887935ESR2HU

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA887935ESR2HU at dilution of 1:100

CSB-PA887935ESR2HU

Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA887935ESR2HU at dilution of 1:100

PDGFD Antibodies

PDGFD for Homo sapiens (Human)

PDGFD for Mus musculus (Mouse)

PDGFD Proteins

PDGFD Proteins for Pongo abelii (Sumatran orangutan)

PDGFD Proteins for Oryctolagus cuniculus (Rabbit)

PDGFD Proteins for Mus musculus (Mouse)

PDGFD Proteins for Rattus norvegicus (Rat)

PDGFD Proteins for Homo sapiens (Human)