P2RY12

P2RY12，即嘌呤能受体P2Y12，别名HORK3、P2Y12、ADPG-R、BDPLT8、SP1999。P2RY12通过与ADP结合，激活Gi蛋白，进而抑制腺苷酸环化酶（AC），减少环磷酸腺苷（cAMP）的生成，影响血小板聚集和血栓形成。P2RY12在血小板激活和血液凝固过程中扮演关键角色，是治疗血栓栓塞和其他凝血障碍的潜在靶点。该基因的突变与血小板型出血性疾病相关，可变剪接导致该基因的多个转录变异体。

热销产品

Recombinant Human P2Y purinoceptor 12 (P2RY12) (CSB-CF861997HU)

验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

P2RY12 Protein

P2RY12 Proteins

P2RY12 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

产品货号	产品名称	来源
CSB-YP839200MOV1 CSB-EP839200MOV1 CSB-BP839200MOV1 CSB-MP839200MOV1 CSB-EP839200MOV1-B	Recombinant Macaca fascicularis P2Y purinoceptor 12 (P2RY12), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF839200MOV	Recombinant Macaca fascicularis P2Y purinoceptor 12 (P2RY12)	in vitro E.coli expression system

P2RY12 Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP861428MO1 CSB-EP861428MO1 CSB-BP861428MO1 CSB-MP861428MO1 CSB-EP861428MO1-B	Recombinant Mouse P2Y purinoceptor 12 (P2ry12), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF861428MO	Recombinant Mouse P2Y purinoceptor 12 (P2ry12)	in vitro E.coli expression system

P2RY12 Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP861997HU1 CSB-EP861997HU1 CSB-BP861997HU1 CSB-MP861997HU1 CSB-EP861997HU1-B	Recombinant Human P2Y purinoceptor 12 (P2RY12), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF861997HU	Recombinant Human P2Y purinoceptor 12 (P2RY12)	in vitro E.coli expression system
CSB-MP861997HU	Recombinant Human P2Y purinoceptor 12 (P2RY12)-VLPs	Mammalian cell

P2RY12 Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP872110RA1 CSB-EP872110RA1 CSB-BP872110RA1 CSB-MP872110RA1 CSB-EP872110RA1-B	Recombinant Rat P2Y purinoceptor 12 (P2ry12), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF872110RA	Recombinant Rat P2Y purinoceptor 12 (P2ry12)	in vitro E.coli expression system