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NFATC1

NFATC1,即核因子活化T细胞1,别名NFAT2、NFATc、NF-ATC、NF-ATc1.2等。它是一种由NFATC1基因编码的转录因子,主要在免疫细胞如T细胞和B细胞中表达,对免疫应答中的基因转录调控起关键作用。NFATC1的作用机制涉及钙调磷酸酶的激活,导致其从细胞质转移到细胞核,进而调控靶基因的表达。NFATC1参与调节免疫反应、细胞增殖、分化和迁移等过程,对维持免疫系统平衡至关重要。异常的NFATC1表达与多种疾病相关,包括自身免疫疾病、心血管疾病和肿瘤等。

热销产品

NFATC1 Antibody (CSB-PA17827A0Rb)

验证数据

CSB-PA17827A0Rb

IHC image of CSB-PA17827A0Rb diluted at 1:1200 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA17827A0Rb

Immunofluorescent analysis of HepG2 cells using CSB-PA17827A0Rb at dilution of 1: 100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

NFATC1 Antibodies

NFATC1 for Homo sapiens (Human)

NFATC1 Proteins

NFATC1 Proteins for Bos taurus (Bovine)

NFATC1 Proteins for Sus scrofa (Pig)

NFATC1 Proteins for Mus musculus (Mouse)

NFATC1 Proteins for Homo sapiens (Human)