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NCBP2

NCBP2,即核帽结合蛋白亚基2,别名CBC2、CBP20、NIP1等。它是人类基因编码的蛋白质,属于核帽结合蛋白复合物(CBC)的一部分,这个复合物能够与新生前体mRNA的单甲基化5'帽结构结合。NCBP2含有RNA结合蛋白中常见的RNP结构域,并具有帽结合活性。它在pre-mRNA剪接、3'端加工、RNA核输出和无义介导的mRNA衰变等过程中发挥作用。此外,NCBP2还参与了mRNA的出口,通过与ALYREF/THOC4/ALY的相互作用,促进mRNA从核到细胞质的运输。NCBP2对于基因表达的调控、mRNA的加工和运输等过程具有重要的生物学意义。

热销产品

Recombinant Human Nuclear cap-binding protein subunit 2 (NCBP2) (CSB-EP015521HU)

验证数据

CSB-EP015521HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

NCBP2 Antibody (CSB-PA015521ESR1HU)

验证数据

CSB-PA015521ESR1HU

Western blot
All lanes: NCBP2 antibody at 5µg/ml
Lane 1: Hela whole cell lysate
Lane 2: NIH/3T3 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 19, 16, 12 kDa
Observed band size: 19 kDa

CSB-PA015521ESR1HU

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA015521ESR1HU at dilution of 1:100

NCBP2 Antibodies

NCBP2 for Homo sapiens (Human)

NCBP2 Proteins

NCBP2 Proteins for Homo sapiens (Human)