NAT10
NAT10，即N-乙酰基转移酶10，别名ALP、Kre33、NET43。它是由人类NAT10基因编码的核蛋白，属于GNAT家族的乙酰转移酶。NAT10在多种细胞过程中发挥作用，包括RNA的乙酰化修饰、核糖体RNA的生物合成、DNA损伤修复以及mRNA稳定性的维持。其作用机制涉及催化组蛋白和非组蛋白的乙酰化修饰，以及作为RNA结合蛋白，通过在特定RNA分子上添加乙酰基团来调节RNA的稳定性和翻译效率。NAT10参与调控细胞周期、细胞迁移、肿瘤转移、DNA损伤响应以及细胞衰老等重要生命活动。NAT10的异常表达与多种疾病相关，包括癌症、Hutchinson-Gilford早衰综合征、系统性红斑狼疮等。NAT10被认为是多种疾病治疗的潜在靶点。
热销产品
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA088333(NAT10 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA088333(NAT10 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 6%SDS-PAGE, Lysate: 50 μg, Lane 1-3: A549 cells, K562 cells, hela cells, Primary antibody: CSB-PA088333(NAT10 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
NAT10 Antibodies
NAT10 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA015465GA01HU | NAT10 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA088333 | NAT10 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA792051 | NAT10 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA863939LA01HU | NAT10 Antibody | Human | ELISA, WB, IHC, IP |
| CSB-PA863939LB01HU | NAT10 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA863939LC01HU | NAT10 Antibody, FITC conjugated | Human |
NAT10 Proteins
NAT10 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP863939HU CSB-EP863939HU CSB-BP863939HU CSB-MP863939HU CSB-EP863939HU-B |
Recombinant Human N-acetyltransferase 10 (NAT10), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
