MX1
MX1，全称为Interferon-induced GTP-binding protein Mx1，是一种在细胞抗病毒应答中发挥重要作用的蛋白。它也被称为IFI-78K、interferon-inducible protein p78和MxA等。MX1蛋白主要由I型 и II型干扰素诱导产生，能够抑制多种RNA和DNA病毒的复制过程。例如，它可以通过与病毒核衣壳结合并使其失活来抑制流感病毒和乙型肝炎病毒的复制。此外，MX1蛋白还能拮抗轮状病毒和星状病毒的复制。在流感病毒感染中，MX1蛋白能够减少或延迟核衣壳蛋白（NP）的合成，并阻断病毒粒子的内吞途径，从而抑制病毒的复制。MX1蛋白的相关疾病主要包括流感病毒感染和狂犬病等。目前，针对MX1蛋白的药物研发主要集中在抗病毒药物和免疫调节剂等方面。例如，一些研究正在探索MX1蛋白作为抗病毒药物靶点的潜力，以及开发能够增强MX1蛋白抗病毒活性的药物。此外，还有一些研究正在探索MX1蛋白在自身免疫性疾病中的作用，以及开发针对这些疾病的MX1蛋白靶向药物。
热销产品
MX1 Antibody (CSB-PA015249LA01HU)
验证数据
Western Blot
Positive WB detected in: A549 whole cell lysate, NIH/3T3 whole cell lysate, Hela whole cell lysate
All lanes: MX1 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 76, 56 kDa
Observed band size: 76 kDa
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA015249LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA015249LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunoprecipitating MX1 in Hela whole cell lysate
Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA015249LA01HU in Hela whole cell lysate.For western blotting, a HRP-conjugated light chain specific antibody was used as the Secondary antibody (1/50000)
Lane 2: CSB-PA015249LA01HU (4μg) + Hela whole cell lysate (500μg)
Lane 3: Hela whole cell lysate (20μg)
Immunohistochemistry of paraffin-embedded human testicular tissue using CSB-PA015249LA01HU at dilution of 1:100
Human Interferon-induced GTP-binding protein Mx1(MX1) ELISA kit (CSB-EL015249HU)
验证数据
货号：CSB-EL015249HU
规格：96T/48T
灵敏度：3.9 pg/mL
检测范围：15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
MX1 Antibodies
MX1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA015249GA01HU | MX1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA616832 | MX1 Antibody | Human | ELISA,WB |
| CSB-PA015249LA01HU | MX1 Antibody | Human, Mouse | ELISA, WB, IHC, IF, IP |
| CSB-PA015249LB01HU | MX1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA015249LC01HU | MX1 Antibody, FITC conjugated | Human | |
| CSB-PA015249LD01HU | MX1 Antibody, Biotin conjugated | Human | ELISA |
MX1 Proteins
MX1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015249HU CSB-EP015249HU CSB-BP015249HU CSB-MP015249HU CSB-EP015249HU-B |
Recombinant Human Interferon-induced GTP-binding protein Mx1 (MX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MX1 ELISA Kit
MX1 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL015249HU | Human Interferon-induced GTP-binding protein Mx1(MX1) ELISA kit | serum, plasma, urine, tissue homogenates, cell lysates | 3.9 pg/mL |
