MORC3
MORC3，即微管组织蛋白，别名KIAA0136、ZCWCC3、NXP2。它是一种核基质蛋白，具有核基质结合结构域，含有推定的RNA结合位点，对转录调控至关重要。MORC3在免疫细胞中的表达水平较高，且在化疗后正常外周血白细胞中的表达明显上调，表明它可能参与调节细胞存活与细胞凋亡。MORC3通过激活p53并将其定位于早幼粒细胞白血病（PML）核体内，诱导p53依赖的细胞衰老。此外，MORC3还参与DNA损伤修复和表观遗传调控，其异常表达与癌症、自身免疫疾病和骨病相关。MORC3的功能区图谱揭示了它在多种基本生物学过程中的作用，包括信号依赖的染色质重塑和表观遗传调控，促进脂肪生成，参与癌症发生和骨稳态调节。
热销产品
Recombinant Human MORC family CW-type zinc finger protein 3 (MORC3), partial (CSB-EP622753HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP622753HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) MORC3.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP622753HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) MORC3.
MORC3 Proteins
MORC3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP622753HU CSB-BP622753HU CSB-MP622753HU CSB-EP622753HU-B |
Recombinant Human MORC family CW-type zinc finger protein 3 (MORC3), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP622753HU | Recombinant Human MORC family CW-type zinc finger protein 3 (MORC3), partial | E.coli |
