MCRS1
MCRS1，即微球蛋白1，别名P78、MCRS2、MSP58、INO80Q、ICP22BP。MCRS1是Ino80复合体、MLL1复合体及组蛋白乙酰转移酶复合物的一部分，参与组蛋白H4乙酰化、DNA代谢过程的负调控以及蛋白质定位到核仁的正向调节。
MCRS1的异常表达与多种疾病相关，尤其是肿瘤的发生和发展。MCRS1在肺癌、胰腺癌等实体瘤中高表达，并通过调控MHC-I分子的表达影响肿瘤细胞对免疫治疗的敏感性，是新的治疗靶点和预测指标。MCRS1还参与基因转录调节和细胞转化等过程，对恶性肿瘤的发生及发展具有重要影响。
热销产品
MCRS1 Antibody (CSB-PA013611LA01HU)
验证数据
Western blot
All lanes: MCRS1 antibody at 8μg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 52, 54, 51, 32 kDa
Observed band size: 52 kDa
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA013611LA01HU at dilution of 1:100
MCRS1 Antibodies
MCRS1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA013611GA01HU | MCRS1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA013611LA01HU | MCRS1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA013611LB01HU | MCRS1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA013611LC01HU | MCRS1 Antibody, FITC conjugated | Human | |
| CSB-PA013611LD01HU | MCRS1 Antibody, Biotin conjugated | Human | ELISA |
MCRS1 Proteins
MCRS1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP013611HU CSB-EP013611HU CSB-BP013611HU CSB-MP013611HU CSB-EP013611HU-B |
Recombinant Human Microspherule protein 1 (MCRS1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
