MCL1
MCL1，即髓样细胞白血病1蛋白，别名MCL-1。MCL1是一种抗凋亡蛋白，属于Bcl-2家族成员，主要通过与促凋亡Bcl-2蛋白结合来防止细胞凋亡。MCL1在多种细胞类型中表达，尤其在造血干细胞和神经细胞中发挥重要作用。MCL1的作用机制涉及其在细胞内线粒体膜上的定位，通过其BH3结合位点与其他Bcl-2家族成员相互作用，调节细胞生存和凋亡。在细胞应激时，MCL1的表达和稳定性发生变化，从而影响细胞命运。MCL1还参与调节细胞周期、DNA损伤响应、自噬、线粒体动力学和能量代谢等非凋亡过程。MCL1的表达失调与多种疾病的发生发展有关，尤其是在癌症中，MCL1的过表达与肿瘤的发生、不良预后和耐药性密切相关。
热销产品
验证数据
Western Blot analysis of HepG2 cells using Mcl-1 Polyclonal Antibody
Western Blot analysis of NIH-3T3 Jurkat cells using Mcl-1 Polyclonal Antibody
MCL1 Antibodies
MCL1 for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA013588HD01MO | Mcl1 Antibody, Biotin conjugated | Mouse | ELISA |
| CSB-PA013588HA01MO | Mcl1 Antibody | Mouse | ELISA |
MCL1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA013588GA01HU | MCL1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA274877 | MCL1 Antibody | Human | ELISA,WB |
| CSB-PA787977 | MCL1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA003207 | MCL1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA004991 | MCL1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA010105 | Phospho-MCL1 (S159) Antibody | Human,Mouse | WB, IF, ELISA |
| CSB-PA010107 | MCL1 Antibody | Human,Mouse,Monkey | WB, ELISA |
| CSB-PA256752 | MCL1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA438059 | MCL1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA03829A0Rb | MCL1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA03829B0Rb | MCL1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA03829C0Rb | MCL1 Antibody, FITC conjugated | Human | |
| CSB-PA03829D0Rb | MCL1 Antibody, Biotin conjugated | Human | ELISA |
MCL1 Proteins
MCL1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP013588MO CSB-BP013588MO CSB-MP013588MO CSB-EP013588MO-B |
Recombinant Mouse Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mcl1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP013588MO | Recombinant Mouse Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mcl1), partial | E.coli |
| CSB-CF013588MO | Recombinant Mouse Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mcl1) | in vitro E.coli expression system |
MCL1 Proteins for Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP385863RIJ CSB-EP385863RIJ CSB-BP385863RIJ CSB-MP385863RIJ CSB-EP385863RIJ-B |
Recombinant Rhodobacter sphaeroides Malyl-CoA lyase (mcl1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MCL1 Proteins for Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP394443RLG CSB-EP394443RLG CSB-BP394443RLG CSB-MP394443RLG CSB-EP394443RLG-B |
Recombinant Rhodobacter sphaeroides Malyl-CoA lyase (mcl1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MCL1 Proteins for Rhodobacter capsulatus (Rhodopseudomonas capsulata)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP466974RLC CSB-EP466974RLC CSB-BP466974RLC CSB-MP466974RLC CSB-EP466974RLC-B |
Recombinant Rhodobacter capsulatus Malyl-CoA lyase (mcl1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MCL1 Proteins for Rhodobacter sphaeroides (strain KD131 / KCTC 12085)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP495428RLH CSB-EP495428RLH CSB-BP495428RLH CSB-MP495428RLH CSB-EP495428RLH-B |
Recombinant Rhodobacter sphaeroides Malyl-CoA lyase (mcl1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MCL1 Proteins for Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP522144RLD CSB-EP522144RLD CSB-BP522144RLD CSB-MP522144RLD CSB-EP522144RLD-B |
Recombinant Rhodobacter capsulatus Malyl-CoA lyase (mcl1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MCL1 Proteins for Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP667039RLF CSB-EP667039RLF CSB-BP667039RLF CSB-MP667039RLF CSB-EP667039RLF-B |
Recombinant Rhodobacter sphaeroides Malyl-CoA lyase (mcl1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MCL1 Proteins for Felis catus (Cat) (Felis silvestris catus)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP768742CA1 CSB-EP768742CA1 CSB-BP768742CA1 CSB-MP768742CA1 CSB-EP768742CA1-B |
Recombinant Cat Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (MCL1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF768742CA | Recombinant Cat Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (MCL1) | in vitro E.coli expression system |
MCL1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP810233DO1 CSB-EP810233DO1 CSB-BP810233DO1 CSB-MP810233DO1 CSB-EP810233DO1-B |
Recombinant Dog Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (MCL1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF810233DO | Recombinant Dog Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (MCL1) | in vitro E.coli expression system |
MCL1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP874875SXV CSB-EP874875SXV CSB-BP874875SXV CSB-MP874875SXV CSB-EP874875SXV-B |
Recombinant Schizosaccharomyces pombe Minichromosome loss protein 1 (mcl1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
