MBTPS1
MBTPS1，即膜结合转录因子肽酶位点1。别名S1P、PCSK8、SEDKF、SKI-1。它是一种由人类基因组编码的蛋白质，属于枯草杆菌蛋白酶样原蛋白转化酶家族的成员。MBTPS1在内质网中以不活跃的前体形式合成，经过高尔基体的自催化加工后变得活跃。其作用机制主要是通过在非碱性残基处切割底物，调节胆固醇或脂质稳态。MBTPS1在多种细胞过程中发挥作用，包括调节胆固醇和脂肪酸的合成、促进抗体分泌细胞的生成以及在内质网应激反应中激活ATF6。MBTPS1参与调控细胞的增殖、分化、脂质代谢和内质网应激反应。该基因的突变可能与溶酶体功能障碍相关，且与某些遗传性疾病如Kondo-Fu类型的粘多糖贮积症和脊柱-干骺端发育不良有关。
热销产品
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
MBTPS1 Antibody (CSB-PA237035ESR2HU)
验证数据
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA237035ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA237035ESR2HU at dilution of 1:100
MBTPS1 Antibodies
MBTPS1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA237035 | MBTPS1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA070134 | MBTPS1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA237035ESR1HU | MBTPS1 Antibody | Human | ELISA, IHC |
| CSB-PA237035ESR2HU | MBTPS1 Antibody | Human | ELISA, IHC |
| CSB-PA617930LA01HU | MBTPS1 Antibody | Human | ELISA, IHC |
| CSB-PA617930LA11HU | MBTPS1 Antibody | Human | ELISA, IF |
| CSB-PA617930LD01HU | MBTPS1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA617930LD11HU | MBTPS1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA617930LC01HU | MBTPS1 Antibody, FITC conjugated | Human | |
| CSB-PA617930LC11HU | MBTPS1 Antibody, FITC conjugated | Human | |
| CSB-MA617930A0m | MBTPS1 Monoclonal Antibody | Human | ELISA, WB, FC |
MBTPS1 Proteins
MBTPS1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP617930HU CSB-BP617930HU CSB-MP617930HU CSB-EP617930HU-B |
Recombinant Human Membrane-bound transcription factor site-1 protease (MBTPS1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP617930HU | Recombinant Human Membrane-bound transcription factor site-1 protease (MBTPS1), partial | E.coli |
| CSB-EP617930HU1 | Recombinant Human Membrane-bound transcription factor site-1 protease (MBTPS1), partial | E.coli |
MBTPS1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP893411RA CSB-EP893411RA CSB-BP893411RA CSB-MP893411RA CSB-EP893411RA-B |
Recombinant Rat Membrane-bound transcription factor site-1 protease (Mbtps1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MBTPS1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP895279MO CSB-EP895279MO CSB-BP895279MO CSB-MP895279MO CSB-EP895279MO-B |
Recombinant Mouse Membrane-bound transcription factor site-1 protease (Mbtps1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
