LRP4
LRP4,即低密度脂蛋白受体相关蛋白4,别名CLSS、CMS17、LRP-4、LRP10、MEGF7、SOST2等。它来源于人类基因编码,是低密度脂蛋白受体(LDLR)家族的一员。LRP4的作用机制复杂,涉及对MuSK激活、AChR聚集和神经肌肉接头(NMJ)形成的调控。LRP4对神经肌肉接头突触前正常投射及成年后突触末梢的维持有重要功能,同时也与重症肌无力(MG)等疾病的发病机制密切相关,为相关疾病的研究和治疗提供了新的视角。
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验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
LRP4 Antibody (CSB-PA013099ESR1HU)
验证数据

Western blot
All lanes: LRP4 antibody at 1.39µg/ml + PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 213 kDa
Observed band size: 213 kDa

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA013099ESR1HU at dilution of 1:100
LRP4 Antibodies
LRP4 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA013099ESR1HU | LRP4 Antibody | Human | ELISA, WB, IHC |
CSB-PA013099ESR2HU | LRP4 Antibody | Human | ELISA, IHC |
LRP4 Proteins
LRP4 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP013099HU | Recombinant Human Low-density lipoprotein receptor-related protein 4 (LRP4), partial | Yeast |
CSB-EP013099HU | Recombinant Human Low-density lipoprotein receptor-related protein 4 (LRP4), partial | E.coli |
LRP4 ELISA Kit
LRP4 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E17518h | Human low-density lipoprotein-receptor-related protein 4(LRP-4)ELISA Kit | serum, plasma, tissue homogenates | 15.6 pg/mL |