KCNQ3
KCNQ3,即钾电压门控通道亚家族Q成员3,别名Kv7.3、KCNQ2-like protein、KCNQ3 potassium channel等。KCNQ3基因位于人类3号染色体上,编码的蛋白质属于电压门控钾离子通道家族成员。KCNQ3的作用机制是通过形成钾离子通道,调节钾离子的流动,从而控制细胞膜电位,维持神经元的兴奋性。在神经系统中,KCNQ3与KCNQ2或KCNQ5等亚单位形成异源四聚体,构成M型钾通道,参与调节神经元的静息膜电位和动作电位的复极化过程。KCNQ3功能异常与多种神经系统疾病相关,如癫痫、神经性疼痛等。此外,KCNQ3的表达和功能也与肿瘤的发生发展有关,是研究和治疗相关疾病的潜在靶点。
热销产品
KCNQ3 Antibody (CSB-PA012091LA01HU)
验证数据

Western Blot
Positive WB detected in: K562 whole cell lysate(30µg), THP-1 whole cell lysate(30µg), JK whole cell lysate(30µg), HepG2 whole cell lysate(30µg), A549 whole cell lysate(30µg), Mouse Brain tissue lysate(30µg),Rat Brain tissue lysate(30µg)
All lanes: KCNQ3 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/20000 dilution
Predicted band size: 97,85,90,100 kDa
Observed band size: 100 kDa
Exposure time:120s

Immunofluorescence staining of HepG2 cell with CSB-PA012091LA01HU at 1:10, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunofluorescence staining of HepG2 cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunofluorescence staining of SH-SY5Y cell with CSB-PA012091LA01HU at 1:10, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunofluorescence staining of SH-SY5Y cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
KCNQ3 Antibodies
KCNQ3 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA012091LA01HU | KCNQ3 Antibody | Human | ELISA, WB, IF |
CSB-PA012091LB01HU | KCNQ3 Antibody, HRP conjugated | Human | ELISA |
CSB-PA012091LC01HU | KCNQ3 Antibody, FITC conjugated | Human | |
CSB-PA012091LD01HU | KCNQ3 Antibody, Biotin conjugated | Human | ELISA |
KCNQ3 Proteins
KCNQ3 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP012091HU CSB-EP012091HU CSB-BP012091HU CSB-MP012091HU CSB-EP012091HU-B |
Recombinant Human Potassium voltage-gated channel subfamily KQT member 3 (KCNQ3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |