Your Good Partner in Biology Research

KCNQ3

KCNQ3,即钾电压门控通道亚家族Q成员3,别名Kv7.3、KCNQ2-like protein、KCNQ3 potassium channel等。KCNQ3基因位于人类3号染色体上,编码的蛋白质属于电压门控钾离子通道家族成员。KCNQ3的作用机制是通过形成钾离子通道,调节钾离子的流动,从而控制细胞膜电位,维持神经元的兴奋性。在神经系统中,KCNQ3与KCNQ2或KCNQ5等亚单位形成异源四聚体,构成M型钾通道,参与调节神经元的静息膜电位和动作电位的复极化过程。KCNQ3功能异常与多种神经系统疾病相关,如癫痫、神经性疼痛等。此外,KCNQ3的表达和功能也与肿瘤的发生发展有关,是研究和治疗相关疾病的潜在靶点。

热销产品

KCNQ3 Antibody (CSB-PA012091LA01HU)

验证数据

CSB-PA012091LA01HU

Western Blot
Positive WB detected in: K562 whole cell lysate(30µg), THP-1 whole cell lysate(30µg), JK whole cell lysate(30µg), HepG2 whole cell lysate(30µg), A549 whole cell lysate(30µg), Mouse Brain tissue lysate(30µg),Rat Brain tissue lysate(30µg)
All lanes: KCNQ3 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/20000 dilution
Predicted band size: 97,85,90,100 kDa
Observed band size: 100 kDa
Exposure time:120s

CSB-PA012091LA01HU

Immunofluorescence staining of HepG2 cell with CSB-PA012091LA01HU at 1:10, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA012091LA01HU

Immunofluorescence staining of HepG2 cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA012091LA01HU

Immunofluorescence staining of SH-SY5Y cell with CSB-PA012091LA01HU at 1:10, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA012091LA01HU

Immunofluorescence staining of SH-SY5Y cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

KCNQ3 Antibodies

KCNQ3 for Homo sapiens (Human)

KCNQ3 Proteins

KCNQ3 Proteins for Homo sapiens (Human)