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ITGA2

ITGA2,即整合素α2亚基,别名CD49b、GPIa、HPA-5、VLA-2,是一种150 kDa的膜表面糖蛋白,在多种细胞类型中表达,如血小板、肠上皮细胞、NK细胞、上皮细胞和活化T细胞等。
ITGA2的作用机制是与CD29(整合素β1)非共价结合形成异质二聚体VLA-2,即血小板糖蛋白Ia/IIa (CD49b/CD29),介导成熟巨核细胞和血小板与胶原之间的粘附。ITGA2在细胞外基质细胞粘附中起着重要作用,参与细胞粘附、迁移、增殖和信号传导等过程,对维持组织结构和功能完整性至关重要。异常的ITGA2表达与多种疾病相关,包括多种动脉疾病、血小板疾病、糖尿病等。

热销产品

Recombinant Human Integrin alpha-2 (ITGA2), partial (CSB-EP011864HUb0)

验证数据

CSB-EP011864HUb0

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ITGA2 Antibody (CSB-PA006197)

验证数据

CSB-PA006197

Western Blot analysis of 3T3 cells using Integrin α2 Polyclonal Antibody

CSB-PA006197

Western Blot analysis of NIH-3T3 cells using Integrin α2 Polyclonal Antibody

Human Integrin alpha-2(ITGA2) ELISA kit (CSB-EL011864HU)

验证数据

CSB-EL011864HU 标准曲线

货号:CSB-EL011864HU

规格:96T/48T

灵敏度:0.058 ng/mL

检测范围:0.235 ng/mL-15 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ITGA2 Antibodies

ITGA2 for Homo sapiens (Human)

ITGA2 Proteins

ITGA2 Proteins for Homo sapiens (Human)

ITGA2 Proteins for Bos taurus (Bovine)

ITGA2 Proteins for Mus musculus (Mouse)

ITGA2 ELISA Kit

ITGA2 ELISA Kit for Homo sapiens (Human)