INSR
INSR，即胰岛素受体（Insulinreceptor），别名IGFR、IRR。INSR由人类INSR基因编码，该基因位于19号染色体的p13.2区域。INSR是一种跨膜受体酪氨酸激酶，属于受体酪氨酸激酶家族的Ⅱ型亚家族。当胰岛素与其受体结合后，通过一系列结构构象变化，激活胞内酪氨酸激酶活性，起始胞内信号传导。
INSR在调节血糖水平中发挥关键作用，促进葡萄糖进入肝细胞、肌细胞、脂肪细胞及其他组织细胞合成糖原，降低血糖，并促进脂肪及蛋白质的合成。INSR的异常可能导致多种代谢性疾病，包括糖尿病和胰岛素抵抗。
热销产品
Recombinant Human Insulin receptor (INSR),Partial (CSB-EP011753HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
INSR Antibody (CSB-PA011753LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA011753LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA011753LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA011753LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
INSR Antibodies
INSR for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA011753GA01HU | INSR Antibody | Human,Rat | ELISA,WB,IP |
| CSB-PA202534 | Phospho-INSR (Tyr1361) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA203919 | Phospho-INSR (Tyr1355) Antibody | Human | ELISA,WB |
| CSB-PA945193 | INSR (Ab-1375) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA994563 | Phospho-INSR (Thr1375) Antibody | Human,Mouse | ELISA,WB |
| CSB-PA003043 | INSR Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA011224 | Phospho-INSR (T1375) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA011225 | Phospho-INSR (Y1355) Antibody | Human | WB, IHC, ELISA |
| CSB-PA011226 | Phospho-INSR (Y1361) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA011227 | INSR Antibody | Human,Mouse,Rat | IF, ELISA |
| CSB-PA011228 | INSR Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA011229 | INSR Antibody | Human | IHC, IF, ELISA |
| CSB-PA410086 | INSR Antibody | Human | IHC,ELISA |
| CSB-PA011753LA01HU | INSR Antibody | Human | ELISA, IHC, IF |
| CSB-PA011753LB01HU | INSR Antibody, HRP conjugated | Human | ELISA |
| CSB-PA011753LC01HU | INSR Antibody, FITC conjugated | Human | |
| CSB-PA011753LD01HU | INSR Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA155156A0HU | INSR Recombinant Monoclonal Antibody | Human | ELISA, IF |
INSR Proteins
INSR Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011753MO1 CSB-EP011753MO1 CSB-BP011753MO1 CSB-MP011753MO1 CSB-EP011753MO1-B |
Recombinant Mouse Insulin receptor (Insr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INSR Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011753RA CSB-EP011753RA1 CSB-BP011753RA1 CSB-MP011753RA1 CSB-EP011753RA-B |
Recombinant Rat Insulin receptor (Insr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INSR Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011753HU CSB-BP011753HU CSB-MP011753HU CSB-EP011753HU-B |
Recombinant Human Insulin receptor (INSR), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011753HU | Recombinant Human Insulin receptor (INSR) | in vitro E.coli expression system |
| CSB-EP011753HU | Recombinant Human Insulin receptor (INSR),Partial | E.coli |
INSR Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011753XBE CSB-EP011753XBE CSB-BP011753XBE CSB-MP011753XBE CSB-EP011753XBE-B |
Recombinant Xenopus laevis Insulin receptor (insr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INSR Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011753MOW CSB-EP011753MOW CSB-BP011753MOW CSB-MP011753MOW CSB-EP011753MOW-B |
Recombinant Macaca mulatta Insulin receptor (INSR) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
