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HTR2A

HTR2A,即5-羟色胺2A受体,别名HTR2、5-hydroxytryptamine receptor 2A、5-HT-2、5-HT-2A、Serotonin receptor 2A。它是一种G蛋白偶联受体,属于血清素受体家族成员,由HTR2A基因编码。HTR2A在大脑中广泛分布,尤其在前额叶皮质、海马体和纹状体等区域。HTR2A的作用机制主要是通过与5-羟色胺(5-HT)等配体结合,激活G蛋白,进而调节下游效应子的活性,如腺苷酸环化酶,影响细胞内的信号传递。HTR2A参与调节多种生理功能,包括情绪、认知、疼痛感知、血管收缩等。HTR2A的活性也与多种疾病的发生发展密切相关,如精神分裂症、强迫症、抑郁症、偏头痛、帕金森病等。HTR2A是多种药物作用的靶点,包括抗精神病药、抗抑郁药和偏头痛治疗药物。例如,某些抗精神病药物通过拮抗HTR2A受体发挥作用,而某些抗抑郁药则可能通过影响5-羟色胺的再摄取来间接调节HTR2A受体的功能。因此,HTR2A是精神药理学研究和相关疾病治疗中的一个重要靶点 。

热销产品

HTR2A Antibody (CSB-PA010887LA01HU)

验证数据

CSB-PA010887LA01HU

Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA010887LA01HU at dilution of 1:100

CSB-PA010887LA01HU

Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA010887LA01HU at dilution of 1:100

CSB-PA010887LA01HU

Immunofluorescent analysis of PC-3 cells using CSB-PA010887LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

HTR2A Antibodies

HTR2A for Homo sapiens (Human)

HTR2A Proteins

HTR2A Proteins for Rattus norvegicus (Rat)

HTR2A Proteins for Mus musculus (Mouse)

HTR2A Proteins for Cavia porcellus (Guinea pig)

HTR2A Proteins for Homo sapiens (Human)

HTR2A Proteins for Sus scrofa (Pig)

HTR2A Proteins for Macaca mulatta (Rhesus macaque)

HTR2A Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

HTR2A Proteins for Pongo pygmaeus (Bornean orangutan)

HTR2A Proteins for Bos taurus (Bovine)

HTR2A ELISA Kit

HTR2A ELISA Kit for Rattus norvegicus (Rat)