HTR1A
HTR1A，即5-羟色胺1A受体，别名ADRB2RL1、ADRBRL1、5-hydroxytryptamine receptor 1A、5-HT-1A、5-HT1A、G-21、Serotonin receptor 1A。它是一种G蛋白偶联受体，广泛分布于大脑中接收来自中缝核的血清素能信号的区域，是中枢神经系统中血清素信号传导的关键介质。HTR1A由HTR1A基因编码，其作用机制主要是通过与5-羟色胺（5-HT）等配体结合，激活G蛋白，进而调节下游效应子的活性，如腺苷酸环化酶，影响细胞内的信号传递。HTR1A在生物学上的意义非常广泛，它参与调节多种生理功能，包括情绪、睡眠、疼痛感知、认知功能以及自主神经系统的调节等。HTR1A的活性也与多种疾病的发生发展密切相关，如抑郁症、焦虑症、偏头痛、帕金森病、肠易激综合症、癫痫、产后抑郁、焦虑症、睡眠障碍、先天性中枢性低通气综合征、进食障碍、酒精依赖、内源性抑郁、神经性厌食症、神经性贪食症、病理性赌博、马查多-约瑟夫病（一种遗传性运动障碍）、慢性疼痛、无痛症、偏头痛无先兆型等。因此，HTR1A是精神药理学研究和相关疾病治疗中的一个重要靶点 。
热销产品
HTR1A Antibody (CSB-PA010881LA01HU)
验证数据
Immunohistochemistry analysis of human small intestine tissue using CSB-PA010881LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA010881LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
HTR1A Antibodies
HTR1A for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA004142 | HTR1A Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA830794 | HTR1A Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA109594 | HTR1A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA010881LA01HU | HTR1A Antibody | Human | ELISA, IHC, IF |
| CSB-PA010881LC01HU | HTR1A Antibody, FITC conjugated | Human | |
| CSB-PA010881LD01HU | HTR1A Antibody, Biotin conjugated | Human | ELISA |
HTR1A Proteins
HTR1A Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP010881RA1 CSB-EP010881RA1 CSB-BP010881RA1 CSB-MP010881RA1 CSB-EP010881RA1-B |
Recombinant Rat 5-hydroxytryptamine receptor 1A (Htr1a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010881RA | Recombinant Rat 5-hydroxytryptamine receptor 1A (Htr1a) | in vitro E.coli expression system |
HTR1A Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP010881HU1 CSB-EP010881HU1 CSB-BP010881HU1 CSB-MP010881HU1 CSB-EP010881HU1-B |
Recombinant Human 5-hydroxytryptamine receptor 1A (HTR1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010881HU | Recombinant Human 5-hydroxytryptamine receptor 1A (HTR1A) | in vitro E.coli expression system |
HTR1A Proteins for Equus caballus (Horse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP610011HO1 CSB-EP610011HO1 CSB-BP610011HO1 CSB-MP610011HO1 CSB-EP610011HO1-B |
Recombinant Horse 5-hydroxytryptamine receptor 1A (HTR1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF610011HO | Recombinant Horse 5-hydroxytryptamine receptor 1A (HTR1A) | in vitro E.coli expression system |
HTR1A Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP727053MO1 CSB-EP727053MO1 CSB-BP727053MO1 CSB-MP727053MO1 CSB-EP727053MO1-B |
Recombinant Mouse 5-hydroxytryptamine receptor 1A (Htr1a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF727053MO | Recombinant Mouse 5-hydroxytryptamine receptor 1A (Htr1a) | in vitro E.coli expression system |
HTR1A Proteins for Vulpes vulpes (Red fox)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP751082VFW1 CSB-EP751082VFW1 CSB-BP751082VFW1 CSB-MP751082VFW1 CSB-EP751082VFW1-B |
Recombinant Vulpes vulpes 5-hydroxytryptamine receptor 1A (HTR1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF751082VFW | Recombinant Vulpes vulpes 5-hydroxytryptamine receptor 1A (HTR1A) | in vitro E.coli expression system |
HTR1A Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP757858DO1 CSB-EP757858DO1 CSB-BP757858DO1 CSB-MP757858DO1 CSB-EP757858DO1-B |
Recombinant Dog 5-hydroxytryptamine receptor 1A (HTR1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF757858DO | Recombinant Dog 5-hydroxytryptamine receptor 1A (HTR1A) | in vitro E.coli expression system |
HTR1A Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP836541XBE1 CSB-EP836541XBE1 CSB-BP836541XBE1 CSB-MP836541XBE1 CSB-EP836541XBE1-B |
Recombinant Xenopus laevis 5-hydroxytryptamine receptor 1A (htr1a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF836541XBE | Recombinant Xenopus laevis 5-hydroxytryptamine receptor 1A (htr1a) | in vitro E.coli expression system |
HTR1A Proteins for Gorilla gorilla gorilla (Lowland gorilla)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP878793GGZ1 CSB-EP878793GGZ1 CSB-BP878793GGZ1 CSB-MP878793GGZ1 CSB-EP878793GGZ1-B |
Recombinant Gorilla gorilla gorilla 5-hydroxytryptamine receptor 1A (HTR1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF878793GGZ | Recombinant Gorilla gorilla gorilla 5-hydroxytryptamine receptor 1A (HTR1A) | in vitro E.coli expression system |
HTR1A Proteins for Pongo pygmaeus (Bornean orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP885635EXP1 CSB-EP885635EXP1 CSB-BP885635EXP1 CSB-MP885635EXP1 CSB-EP885635EXP1-B |
Recombinant Pongo pygmaeus 5-hydroxytryptamine receptor 1A (HTR1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF885635EXP | Recombinant Pongo pygmaeus 5-hydroxytryptamine receptor 1A (HTR1A) | in vitro E.coli expression system |
HTR1A Proteins for Pan troglodytes (Chimpanzee)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP889023EQV1 CSB-EP889023EQV1 CSB-BP889023EQV1 CSB-MP889023EQV1 CSB-EP889023EQV1-B |
Recombinant Pan troglodytes 5-hydroxytryptamine receptor 1A (HTR1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF889023EQV | Recombinant Pan troglodytes 5-hydroxytryptamine receptor 1A (HTR1A) | in vitro E.coli expression system |
