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GZMK

GZMK,即颗粒酶M,别名Granzyme K、Gzmk。它是一种由GZMK基因编码的丝氨酸蛋白酶,属于颗粒酶家族成员,在细胞毒性T淋巴细胞(CTL)和自然杀伤(NK)细胞中表达。GZMK的作用机制涉及与细胞毒性颗粒中的其他颗粒酶协同作用,通过诱导靶细胞凋亡来发挥其细胞毒性作用,参与免疫应答过程。GZMK的表达和活性在某些疾病中可能发生改变,例如在自身免疫性疾病和肿瘤中。因此,GZMK是免疫学研究和相关疾病治疗中的一个潜在靶点。

热销产品

Recombinant Human Granzyme K (GZMK) (CSB-EP010084HU)

验证数据

CSB-EP010084HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

GZMK Antibody (CSB-PA010084LA01HU)

验证数据

CSB-PA010084LA01HU

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA010084LA01HU at dilution of 1:100

CSB-PA010084LA01HU

Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA010084LA01HU at dilution of 1:100

CSB-PA010084LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA010084LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

GZMK Antibodies

GZMK for Homo sapiens (Human)

GZMK Proteins

GZMK Proteins for Homo sapiens (Human)