GSK3A
GSK3A，即糖原合酶激酶3α，别名GSK-3alpha、serine/threonine-proteinkinaseGSK3A。它在人体中广泛表达，尤其在大脑和睾丸中的表达量较高。GSK3A的作用机制涉及其作为多功能Ser/Thr蛋白激酶，控制多种调节蛋白，包括糖原合酶和转录因子，如JUN。它在Wnt和PI3K信号通路中发挥作用，并调节与阿尔茨海默病相关的β-淀粉样肽的产生。GSK3A影响细胞增殖、分化、凋亡等重要生理过程，与多种疾病的发生发展相关，包括神经退行性疾病、糖尿病、炎症性疾病和癌症。因此，GSK3A是一个重要的调控分子，其活性的调节为多种治疗策略提供了潜在的靶点。
热销产品
GSK3A Antibody (CSB-PA05369A0Rb)
验证数据
Western Blot
Positive WB detected in: HepG2 whole cell lysate
All lanes: GSK3A antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 51 kDa
Observed band size: 51 kDa
Immunofluorescent analysis of Hela cells using CSB-PA05369A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
GSK3A Antibodies
GSK3A for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA009962GA01HU | GSK3A Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA144022 | Phospho-GSK3A (Ser21) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA282922 | GSK3A (Ab-21) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA205981 | GSK3A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA000534 | Phospho-GSK3A (S21) Antibody | Human,Mouse,Rat | WB, IHC, IP, ELISA |
| CSB-PA002836 | GSK3A Antibody | Human,Mouse,Rat | WB, IHC, IP, ELISA |
| CSB-PA147596 | GSK3A Antibody | Human | ELISA,IHC |
| CSB-PA932427 | GSK3A Antibody | Human | ELISA,IHC |
| CSB-PA05369A0Rb | GSK3A Antibody | Human | ELISA, WB, IF |
| CSB-PA05369D0Rb | GSK3A Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA009962A216phHU | Phospho-GSK3A/GSK3B (Y216 + Y279) Recombinant Monoclonal Antibody | Human | ELISA, IHC |
GSK3A Proteins
GSK3A Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009962RA CSB-EP009962RA CSB-BP009962RA CSB-MP009962RA CSB-EP009962RA-B |
Recombinant Rat Glycogen synthase kinase-3 alpha (Gsk3a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSK3A Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009962HU CSB-EP009962HU CSB-BP009962HU CSB-MP009962HU CSB-EP009962HU-B |
Recombinant Human Glycogen synthase kinase-3 alpha (GSK3A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GSK3A Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP649920MO CSB-EP649920MO CSB-BP649920MO CSB-MP649920MO CSB-EP649920MO-B |
Recombinant Mouse Glycogen synthase kinase-3 alpha (Gsk3a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
