GPR119
GPR119，即G蛋白偶联受体119，别名Glucose-dependent insulinotropic receptor，是一种G蛋白偶联受体（GPCR）超家族中的孤儿受体，主要分布在胰岛β细胞和胃肠道L细胞。GPR119的作用机制是通过与内源性配体如油酰乙醇酰胺和其他含有油酸的内源性脂质结合来激活，进而刺激胰高血糖素样肽-1（GLP-1）和葡萄糖依赖性促胰岛素释放多肽（GIP）的分泌，这两种激素对于调控体内糖代谢平衡具有重要作用。GPR119的激活可以促进葡萄糖依赖的胰岛素分泌，增加肠道分泌的肠促胰岛素激素，是治疗糖尿病、脂肪肝和肥胖症等代谢性疾病的潜在药物靶点。
热销产品
GPR119 Antibody (CSB-PA007283)
验证数据
Western Blot analysis of COLO cells using GPR119 Polyclonal Antibody
Western blot analysis of SH-SY5Y mouse-kidney lysis using GPR119 antibody.
GPR119 Antibodies
GPR119 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA007283 | GPR119 Antibody | Human | WB, IF, ELISA |
GPR119 Proteins
GPR119 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP752652RA1 CSB-EP752652RA1 CSB-BP752652RA1 CSB-MP752652RA1 CSB-EP752652RA1-B |
Recombinant Rat Glucose-dependent insulinotropic receptor (Gpr119), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF752652RA | Recombinant Rat Glucose-dependent insulinotropic receptor (Gpr119) | in vitro E.coli expression system |
GPR119 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP766514MO1 CSB-EP766514MO1 CSB-BP766514MO1 CSB-MP766514MO1 CSB-EP766514MO1-B |
Recombinant Mouse Glucose-dependent insulinotropic receptor (Gpr119), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF766514MO | Recombinant Mouse Glucose-dependent insulinotropic receptor (Gpr119) | in vitro E.coli expression system |
GPR119 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP840575HU1 CSB-EP840575HU1 CSB-BP840575HU1 CSB-MP840575HU1 CSB-EP840575HU1-B |
Recombinant Human Glucose-dependent insulinotropic receptor (GPR119), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF840575HU | Recombinant Human Glucose-dependent insulinotropic receptor (GPR119) | in vitro E.coli expression system |
