GDF2
GDF2,即生长分化因子2,别名BMP-9、BMP9,属于转化生长因子β超家族(TGF-beta superfamily)中的BMP亚群成员。GDF2主要通过与ALK1等受体结合,传递信号,从而调节多种胚胎和成体组织的发育和功能。GDF2的作用机制涉及与ALK1等受体的结合,激活下游的Smad蛋白,进而影响基因表达。GDF2在肝脏非实质细胞中合成分泌,能够促进脂质代谢并抑制葡萄糖生成。它在胚胎中枢神经系统中对胆碱能神经元表型的发育和维持起着重要作用,同时也诱导间充质干细胞分化为软骨细胞系。GDF2的功能还包括调节血管生成、影响内皮细胞增殖以及参与骨骼和软骨的发育。GDF2的异常表达与遗传性出血性毛细血管扩张症相关。
热销产品
Recombinant Human Growth/differentiation factor 2 (GDF2) (CSB-EP892325HU1)
验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
GDF2 Antibody (CSB-PA892325LA01HU)
验证数据

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA892325LA01HU at dilution of 1:100
GDF2 Antibodies
GDF2 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA892325GA01HU | GDF2 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA886231 | GDF2 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA356766 | GDF2 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA892325LA01HU | GDF2 Antibody | Human | ELISA, IHC |
CSB-PA892325LD01HU | GDF2 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA892325LC01HU | GDF2 Antibody, FITC conjugated | Human | |
CSB-PA892325LB01HU | GDF2 Antibody, HRP conjugated | Human | ELISA |
GDF2 Proteins
GDF2 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP892325HU1 | Recombinant Human Growth/differentiation factor 2 (GDF2), partial | Yeast |
CSB-EP892325HU1 | Recombinant Human Growth/differentiation factor 2 (GDF2) | E.coli |
GDF2 ELISA Kit
GDF2 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E11769h | Human growth differentiation factor 2,GDF2 ELISA Kit | serum, plasma,tissue homogenates | 0.98 pg/mL |