GABRB1
GABRB1，即γ-氨基丁酸A型受体亚基beta1，别名DEE45、EIEE45等。它位于人类第4号染色体的4p12区域，属于GABA受体家族中的一员。GABRB1的作用机制是通过与GABA结合，调节氯离子通道的开启，导致神经元细胞膜的超极化，从而降低神经元的兴奋性，产生抑制性突触后电位。GABRB1在中枢神经系统中调节最快的抑制性突触传递，对于维持神经系统的正常功能至关重要。其变异与精神分裂症的病理学有关，并可能与癫痫、酒精依赖、双相情感障碍等疾病的发生发展相关。
热销产品
GABRB1 Antibody (CSB-PA554723)
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA554723(GABRB1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA554723(GABRB1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
GABRB1 Antibodies
GABRB1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA009146GA01HU | GABRB1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA620050 | GABRB1 (Ab-434) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA000669 | Phospho-GABRB1 (S434) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA008556 | GABRB1 Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA554723 | GABRB1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA086437 | GABRB1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
GABRB1 Proteins
GABRB1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP009146HU CSB-EP009146HU CSB-BP009146HU CSB-MP009146HU CSB-EP009146HU-B |
Recombinant Human Gamma-aminobutyric acid receptor subunit beta-1 (GABRB1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
