FOXA2
FOXA2，即叉头框蛋白A2，别名HNF3B、TCF3B。FOXA2属于叉头类转录因子家族，具有高度保守的翼状螺旋结构域，能够以单体形式结合在靶基因启动子区的DNA序列上。FOXA2通过与染色质的相互作用，改变染色质局部结构来调控基因表达，被称为“先锋因子”。FOXA2在多种生物学过程中起关键作用，包括胚胎发育、细胞分化及疾病发生过程。FOXA2还参与调节肝脏功能基因的表达，包括血浆蛋白、载脂蛋白、凝血因子以及葡萄糖、脂肪酸、氨基酸代谢中的关键代谢酶，参与肝脏发育、器官形成、代谢和稳态维持等多种生物学过程。FOXA2的表达异常与多种疾病相关，包括肝癌、肺癌、胰腺癌、胃癌、甲状腺癌和大肠癌。
热销产品
验证数据
Western blot analysis of extracts from 293, HT29, HepG2 cells using FoxA2(HNF3b) Antibody.
FOXA2 Antibodies
FOXA2 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA146585 | FOXA2 Antibody | Human | ELISA,WB |
| CSB-PA927484 | FOXA2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA167678 | FOXA2 Antibody | Human,Mouse,Rat | ELISA,WB |
FOXA2 Proteins
FOXA2 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP008795MO CSB-EP008795MO CSB-BP008795MO CSB-MP008795MO CSB-EP008795MO-B |
Recombinant Mouse Hepatocyte nuclear factor 3-beta (Foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP008795RA CSB-EP008795RA CSB-BP008795RA CSB-MP008795RA CSB-EP008795RA-B |
Recombinant Rat Hepatocyte nuclear factor 3-beta (Foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Oryzias latipes (Medaka fish) (Japanese ricefish)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP008795OFH CSB-EP008795OFH CSB-BP008795OFH CSB-MP008795OFH CSB-EP008795OFH-B |
Recombinant Oryzias latipes Hepatocyte nuclear factor 3-beta (foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP742473XBF CSB-EP742473XBF CSB-BP742473XBF CSB-MP742473XBF CSB-EP742473XBF-B |
Recombinant Xenopus tropicalis Forkhead box protein A2 (foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP897462HU CSB-EP897462HU CSB-BP897462HU CSB-MP897462HU CSB-EP897462HU-B |
Recombinant Human Hepatocyte nuclear factor 3-beta (FOXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
