EIF3H
EIF3H，全称为真核翻译起始因子3亚基H，是一种参与蛋白质翻译起始过程的蛋白质。它也被称为eIF3h，属于Jab1/Mov34/MPN+蛋白酶家族。EIF3H在多种癌症中表达上调，如结直肠癌和食管鳞状细胞癌，其表达与肿瘤的侵袭性和预后不良相关。研究表明，EIF3H可能通过去泛素化作用稳定Snail蛋白，从而促进肿瘤细胞的侵袭和转移。此外，EIF3H还与Wnt/β-catenin和RAF-MEK-ERK信号通路有关，这些信号通路在肿瘤的发生发展中扮演重要角色。针对EIF3H的药物研发正在进展中，有望成为结直肠癌等癌症治疗的新靶点。
热销产品
EIF3H Antibody (CSB-PA007537ESR1HU)
验证数据
Western blot
All lanes: EIF3H antibody at 6μg/ml
Lane 1: NIH/3T3 whole cell lysate
Lane 2: Rat brain tissue
Lane 3: U251 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 40 kDa
Observed band size: 40 kDa
Immunohistochemistry of paraffin-embedded human epityphlon tissue using CSB-PA007537ESR1HU at dilution of 1:100
EIF3H Antibodies
EIF3H for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA007537GA01HU | EIF3H Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA007537ESR1HU | EIF3H Antibody | Human, Rat | ELISA, WB, IHC |
| CSB-PA007537ESR2HU | EIF3H Antibody | Human, Rat | ELISA, WB, IHC |
| CSB-PA114148 | EIF3H Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA903985 | EIF3H Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
EIF3H Proteins
EIF3H Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007537HU CSB-EP007537HU CSB-BP007537HU CSB-MP007537HU CSB-EP007537HU-B |
Recombinant Human Eukaryotic translation initiation factor 3 subunit H (EIF3H) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
