EFNB2

EFNB2蛋白全称为Ephrin-B2，也被称为LERK5或HTKL，属于ephrin蛋白家族成员。这类蛋白通常以膜结合形式存在，通过与相邻细胞表面的Eph受体相互作用，双向调节细胞黏附、迁移及组织边界形成。EFNB2在胚胎发育阶段对血管网络构建及神经纤维导向具有关键作用，成年后参与组织修复与炎症反应调控。EFNB2异常表达与多种实体瘤的侵袭转移密切相关，尤其在乳腺癌、胶质瘤中可能通过促进新生血管生成加速病情进展。心血管领域研究则提示，EFNB2在动脉粥样硬化斑块的不稳定性和心肌缺血后血管再生过程中扮演双重角色。近年来，针对该蛋白的靶向药物开发聚焦于抑制其介导的病理过程，已有数款单抗类药物进入临床前研究阶段，其中部分药物在动物模型中显示出阻断肿瘤转移的潜力。此外，基于EFNB2结构的生物材料也被探索用于引导神经再生等再生医学领域。

热销产品

EFNB2 Antibody (CSB-PA007466ESR2HU)

验证数据

Western blot
All lanes: EFNB2 antibody at 6μg/ml + Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa

Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA007466ESR2HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA007466ESR2HU at dilution of 1:100

EFNB2 Antibody

EFNB2 Protein

EFNB2 ELISA Kit

EFNB2 Antibodies

EFNB2 for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA007466ESR1HU	EFNB2 Antibody	Human	ELISA, IHC
CSB-PA587215	EFNB2 (Ab-316) Antibody	Human,Mouse	ELISA,WB
CSB-PA077593	EFNB2 (Ab-330) Antibody	Human,Mouse	ELISA,WB,IF
CSB-PA166153	Phospho-EFNB2 (Tyr316) Antibody	Human,Mouse	ELISA,WB
CSB-PA216331	Phospho-EFNB2 (Tyr330) Antibody	Human,Mouse	ELISA,WB
CSB-PA007466ESR2HU	EFNB2 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA035369	EFNB2 Antibody	Human,Mouse	ELISA,IHC

EFNB2 Proteins

EFNB2 Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP007466HU1 CSB-EP007466HU1 CSB-BP007466HU1 CSB-MP007466HU1 CSB-EP007466HU1-B	Recombinant Human Ephrin-B2 (EFNB2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF007466HU	Recombinant Human Ephrin-B2 (EFNB2)	in vitro E.coli expression system