ECI2
ECI2，即烯酰辅酶Aδ-异构酶2，别名ACBD2、DRS1、HCA88、PECI。ECI2是一种关键的线粒体酶，参与不饱和脂肪酸的β-氧化过程。它能够将3-顺式和3-反式烯酰辅酶A酯转化为2-反式烯酰辅酶A中间体。ECI2在脂质代谢中起着重要作用，尤其是在多不饱和脂肪酸的代谢过程中。此外，ECI2还参与过氧化物酶体脂质代谢，可能通过其作为潜在内源性抗氧化剂的能力调节细胞分化、影响细胞信号传导并减少氧化应激。ECI2通过影响肿瘤免疫微环境并抑制结直肠癌的侵袭和转移。ECI2能显著抑制醚脂的产生和IL-8的表达，从而减少中性粒细胞外陷阱（NET）的形成，进而抑制结直肠癌的生长和转移。
热销产品
ECI2 Antibody (CSB-PA527983LA01HU)
验证数据
Western Blot
Positive WB detected in: Rat heart tissue, Mouse heart tissue, Mouse liver tissue
All lanes: ECI2 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 44, 40 kDa
Observed band size: 44 kDa
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA527983LA01HU at dilution of 1:100
ECI2 Antibodies
ECI2 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA017768GA01HU | ECI2 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA002204 | ECI2 Antibody | Human | WB, IHC, ELISA |
| CSB-PA527983LA01HU | ECI2 Antibody | Human, Rat, Mouse | ELISA, WB, IHC |
| CSB-PA527983LB01HU | ECI2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA527983LC01HU | ECI2 Antibody, FITC conjugated | Human | |
| CSB-PA527983LD01HU | ECI2 Antibody, Biotin conjugated | Human | ELISA |
ECI2 Proteins
ECI2 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP527983HU CSB-EP527983HU CSB-BP527983HU CSB-MP527983HU CSB-EP527983HU-B |
Recombinant Human Enoyl-CoA delta isomerase 2, mitochondrial (ECI2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
