DRD4
DRD4，即多巴胺受体D4，别名D(4 dopamine receptor、D(2C dopamine receptor、Dopamine D4 receptor。它是一种G蛋白偶联受体，属于多巴胺受体家族成员之一，由人体细胞自身的DRD4基因编码。DRD4在大脑的边缘系统中表达，特别是与情绪和复杂行为调节相关的区域。其作用机制是通过与多巴胺等配体结合，激活G蛋白，进而抑制腺苷酸环化酶的活性，影响细胞内的信号传递。DRD4参与调节情绪、认知功能、注意力以及成瘾行为等。研究表明，DRD4的多态性与多种心理和神经发育障碍有关，例如注意缺陷多动障碍(ADHD)、精神分裂症、肥胖和吸烟成瘾等。此外，DRD4的活性还与昼夜节律的调节有关，它通过调节视网膜神经节细胞中NPAS2的节律性表达，影响对比敏感度的昼夜节律。因此，DRD4是神经科学研究和相关疾病治疗中的一个潜在靶点。
热销产品
验证数据
Western Blot analysis of K562 cells using D4DR Polyclonal Antibody
Western Blot analysis of K562 cells using D4DR Polyclonal Antibody
DRD4 Antibodies
DRD4 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA002055 | DRD4 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA967891 | DRD4 Antibody | Human | ELISA,WB,IHC |
| CSB-PA695604 | DRD4 Antibody | Human,Mouse | ELISA,WB,IHC |
DRD4 Proteins
DRD4 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007181HU1 CSB-EP007181HU1 CSB-BP007181HU1 CSB-MP007181HU1 CSB-EP007181HU1-B |
Recombinant Human D (4) dopamine receptor (DRD4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007181HU | Recombinant Human D (4) dopamine receptor (DRD4) | in vitro E.coli expression system |
DRD4 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007181RA1 CSB-EP007181RA1 CSB-BP007181RA1 CSB-MP007181RA1 CSB-EP007181RA1-B |
Recombinant Rat D (4) dopamine receptor (Drd4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007181RA | Recombinant Rat D (4) dopamine receptor (Drd4) | in vitro E.coli expression system |
DRD4 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007181MO1 CSB-EP007181MO1 CSB-BP007181MO1 CSB-MP007181MO1 CSB-EP007181MO1-B |
Recombinant Mouse D (4) dopamine receptor (Drd4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007181MO | Recombinant Mouse D (4) dopamine receptor (Drd4) | in vitro E.coli expression system |
DRD4 Proteins for Mustela putorius furo (European domestic ferret) (Mustela furo)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP754376MOH1 CSB-EP754376MOH1 CSB-BP754376MOH1 CSB-MP754376MOH1 CSB-EP754376MOH1-B |
Recombinant Mustela putorius furo D (4) dopamine receptor (DRD4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF754376MOH | Recombinant Mustela putorius furo D (4) dopamine receptor (DRD4) | in vitro E.coli expression system |
