DHCR7
DHCR7，全称为7-脱氢胆固醇还原酶，是一种重要的酶，负责将7-脱氢胆固醇转化为胆固醇。该蛋白有多种别名，如7-DHC还原酶、DHCR7抗体等。它在细胞膜中发挥关键作用，参与胆固醇的代谢。DHCR7的异常可能导致Smith-Lemli-Opitz综合征（SLOS），这是一种影响胆固醇代谢的遗传疾病，患者可能出现认知障碍、面部畸形等症状。近年来，研究人员发现DHCR7在抗病毒感染中也扮演重要角色，因此，针对DHCR7的药物研发成为研究热点。目前，已有一些研究探索了DHCR7抑制剂在治疗病毒感染中的应用潜力。
热销产品
DHCR7 Antibody (CSB-PA006844LA01HU)
验证数据
Western Blot
Positive WB detected in: HepG2 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate
All lanes: DHCR7 antibody at 2.4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa
IHC image of CSB-PA006844LA01HU diluted at 1:600 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
DHCR7 Antibodies
DHCR7 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA900410 | DHCR7 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA110763 | DHCR7 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA006844LA01HU | DHCR7 Antibody | Human | ELISA, WB, IHC |
| CSB-PA006844LD01HU | DHCR7 Antibody, Biotin conjugated | Human | ELISA |
DHCR7 Proteins
DHCR7 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006844HU1 CSB-EP006844HU1 CSB-BP006844HU1 CSB-MP006844HU1 CSB-EP006844HU1-B |
Recombinant Human 7-dehydrocholesterol reductase (DHCR7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF006844HU | Recombinant Human 7-dehydrocholesterol reductase (DHCR7) | in vitro E.coli expression system |
