CYP51A1
CYP51A1，别名CYP51、Lanosterol 14-alpha demethylase、LDM、CYPL，是一种关键的胆固醇合成酶，由CYP51A1基因编码。它在肝脏等组织中表达，负责催化胆固醇生物合成的第一步反应，将羊毛甾醇转化为胆甾醇。CYP51A1还参与多种外源性化合物的代谢，包括药物和环境致癌物。在生物学上，CYP51A1对维持胆固醇稳态至关重要，其异常表达与多种疾病包括癌症有关，是药物代谢和疾病治疗研究中的重要靶点。
热销产品
CYP51A1 Antibody (CSB-PA614993LA01HU)
验证数据
Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: CYP51A1 antibody at 2.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 57, 47 kDa
Observed band size: 57 kDa
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA614993LA01HU at dilution of 1:100
CYP51A1 Antibodies
CYP51A1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA006459GA01HU | CYP51A1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA614993LA01HU | CYP51A1 Antibody | Human | ELISA, WB, IHC |
CYP51A1 Proteins
CYP51A1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP614993HU1 CSB-EP614993HU1 CSB-BP614993HU1 CSB-MP614993HU1 CSB-EP614993HU1-B |
Recombinant Human Lanosterol 14-alpha demethylase (CYP51A1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF614993HU | Recombinant Human Lanosterol 14-alpha demethylase (CYP51A1) | in vitro E.coli expression system |
