CD58
CD58，即细胞表面分化抗原58，别名LFA-3、WLA等。它是一种由CD58基因编码的糖蛋白，主要表达在多种白细胞表面，包括T细胞、B细胞、自然杀伤(NK)细胞等。CD58的作用机制涉及与T细胞表面的CD2受体结合，参与免疫细胞间的相互作用，调节免疫应答。CD58与CD2的相互作用对于T细胞的激活至关重要，影响细胞毒性T细胞的杀伤活性和细胞因子的产生。此外，CD58还参与了免疫逃逸机制，某些病原体如单纯疱疹病毒(HSV)通过表达与CD58相似的蛋白来逃避宿主的免疫监视，是免疫学研究和相关疾病治疗中的一个潜在靶点。
热销产品
CD58 Recombinant Monoclonal Antibody (CSB-RA166177A0HU)
验证数据
Western Blot
Positive WB detected in: Raji whole cell lysate, K562 whole cell lysate, Hela whole cell lysate
All lanes: CD58 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29, 27, 26 kDa
Observed band size: 55-70 kDa
CD58 Antibodies
CD58 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA004946GA01HU | CD58 Antibody | Human | ELISA,WB |
| CSB-PA004946ESR1HU | CD58 Antibody | Human | ELISA, WB, IHC |
| CSB-PA205850 | CD58 Antibody | Human | ELISA,WB |
| CSB-PA001472 | CD58 Antibody | Human | WB, ELISA |
| CSB-PA005227 | CD58 Antibody | Human | WB, ELISA |
| CSB-RA166177A0HU | CD58 Recombinant Monoclonal Antibody | Human | ELISA, WB |
CD58 Proteins
CD58 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004946HU1 CSB-EP004946HU1 CSB-BP004946HU1 CSB-MP004946HU1 CSB-EP004946HU1-B |
Recombinant Human Lymphocyte function-associated antigen 3 (CD58), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004946HU | Recombinant Human Lymphocyte function-associated antigen 3 (CD58) | in vitro E.coli expression system |
