BATF3
BATF3，即碱性亮氨酸拉链ATF样转录因子3，别名JDP1、SNFT、JUNDM1。它是一种由人类BATF3基因编码的转录因子，属于基本亮氨酸拉链蛋白家族。BATF3在多种免疫细胞的发育和功能中发挥作用，尤其在树突状细胞和CD8+T细胞中。其作用机制涉及与JUN蛋白异二聚化，形成转录抑制复合物，调控下游基因的表达，如通过抑制白细胞介素2和基质金属蛋白酶1的转录。BATF3在免疫应答中扮演关键角色，影响T细胞的存活、记忆形成和抗肿瘤免疫反应。BATF3的异常表达与多种疾病相关，包括某些类型的白血病和免疫缺陷。BATF3是研究免疫相关疾病和开发相应治疗策略的重要靶点。
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验证数据
Western blot analysis of mouse-lung mouse-spleen lysis using BATF3 antibody. Antibody was diluted at 1:2000. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200
BATF3 Antibodies
BATF3 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA882082LA01HU | BATF3 Antibody | Human | ELISA, IF |
| CSB-PA882082LC01HU | BATF3 Antibody, FITC conjugated | Human | |
| CSB-PA344549 | BATF3 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
BATF3 Proteins
BATF3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP882082HU CSB-EP882082HU CSB-BP882082HU CSB-MP882082HU CSB-EP882082HU-B |
Recombinant Human Basic leucine zipper transcriptional factor ATF-like 3 (BATF3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
