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ARF1

ARF1,即ADP-核糖基化因子1,别名PVNH8。ARF1由人类ARF1基因编码,该基因位于1号染色体的1q42.13区域。ARF1是一种小GTP结合蛋白,属于Ras超家族成员,其主要功能是刺激霍乱毒素的ADP-核糖基转移酶活性,并作为磷脂酶D的激活剂在囊泡运输中发挥作用。ARF1蛋白定位于高尔基体,在高尔基体内部运输中起着核心作用,通过激活膜上的磷脂酰肌醇4-磷酸酸酯酶和磷脂酰肌醇转移酶,调节膜脂组成。ARF1在细胞内膜系统的功能调节中扮演着关键角色,参与调控囊泡的形成、运输及膜交换过程。ARF1功能异常与多种细胞运输障碍疾病有关,且在某些癌症中的表达异常,可能与肿瘤的生长和转移相关。

热销产品

Recombinant Human ADP-ribosylation factor 1 (ARF1) (CSB-EP001988HUa2)

验证数据

CSB-EP001988HUa2

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ARF1 Antibody (CSB-PA00929A0Rb)

验证数据

CSB-PA00929A0Rb

Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA00929A0Rb at dilution of 1:100

CSB-PA00929A0Rb

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA00929A0Rb at dilution of 1:100

CSB-PA00929A0Rb

Immunofluorescent analysis of Hela cells using CSB-PA00929A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

ARF1 Antibodies

ARF1 for Homo sapiens (Human)

ARF1 Proteins

ARF1 Proteins for Homo sapiens (Human)

ARF1 Proteins for Rattus norvegicus (Rat)

ARF1 Proteins for Mus musculus (Mouse)

ARF1 Proteins for Bos taurus (Bovine)

ARF1 Proteins for Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)

ARF1 Proteins for Salix bakko (Japanese willow)

ARF1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

ARF1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

ARF1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

ARF1 Proteins for Xenopus laevis (African clawed frog)

ARF1 Proteins for Daucus carota (Carrot)

ARF1 Proteins for Chlamydomonas reinhardtii (Chlamydomonas smithii)

ARF1 Proteins for Locusta migratoria (Migratory locust)

ARF1 Proteins for Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

ARF1 Proteins for Zea mays (Maize)

ARF1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

ARF1 Proteins for Plasmodium falciparum (isolate 3D7)

ARF1 Proteins for Plasmodium falciparum

ARF1 Proteins for Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis)

ARF1 Proteins for Plasmodium falciparum (isolate NF54)

ARF1 Proteins for Oryza sativa subsp. japonica (Rice)

ARF1 Proteins for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)