APRIL

APRIL，即增殖诱导配体，别名CD256、TNFSF13。它是一种主要由髓系细胞产生的蛋白质，包括常规树突状细胞、滤泡DC、单核细胞、中性粒细胞和巨噬细胞，活化的B细胞也少量产生APRIL。APRIL的作用机制涉及与其受体TACI、BCMA和HSPG的结合，通过这些相互作用参与调节B细胞的激活、浆细胞的存活以及免疫球蛋白的同种型转换。APRIL在多种生理过程中发挥作用，包括B细胞的成熟、抗体的类别转换以及长寿命浆细胞的形成。此外，APRIL在多种疾病中也有重要作用，包括自身免疫性疾病如系统性红斑狼疮(SLE)和IgA肾病(IgAN)，以及多种类型的癌症，如乳腺癌、结直肠癌和非小细胞肺癌等。APRIL的异常表达与肿瘤细胞的增殖、存活和侵袭有关，使其成为潜在的治疗靶点。

热销产品

TNFSF13 Antibody (CSB-PA023989ESR1HU)

验证数据

Western blot
All lanes: Tumor necrosis factor ligand superfamily member 13 antibody at 10μg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 28, 26, 25, 37, 23 kDa
Observed band size: 28 kDa

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA023989ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA023989ESR1HU at dilution of 1:100

Human a proliferation inducing ligand(APRIL)ELISA Kit (CSB-E15012h)

验证数据

货号：CSB-E15012h

规格：96T/48T

灵敏度：0.195 ng/mL

检测范围：0.78 ng/mL-50 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

APRIL Antibody

APRIL Protein

APRIL ELISA Kit

APRIL Antibodies

APRIL for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA023989GA01HU	TNFSF13 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA023989ESR1HU	TNFSF13 Antibody	Human	ELISA, WB, IHC
CSB-PA023989ESR2HU	TNFSF13 Antibody	Human	ELISA, IHC
CSB-PA244663	TNFSF13 Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA000909	TNFSF13 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA877550	TNFSF13 Antibody	Human,Mouse	ELISA,IHC
CSB-PA935662	TNFSF13 Antibody	Human,Mouse	ELISA,IHC
CSB-PA599200	TNFSF13 Antibody	Human,Mouse	ELISA,IHC
CSB-PA587516	TNFSF13 Antibody	Human,Mouse	ELISA,IHC

APRIL Proteins

APRIL Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP023989HU CSB-EP023989HU CSB-BP023989HU CSB-EP023989HU-B	Recombinant Human Tumor necrosis factor ligand superfamily member 13 (TNFSF13)	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli