Your Good Partner in Biology Research

ALPK1

ALPK1,即α激酶1,别名LAK、ROSAH。它是一种由人类基因编码的非典型丝氨酸/苏氨酸蛋白激酶,与常规蛋白激酶没有序列同源性。ALPK1在多种组织中表达,包括骨髓、皮肤等。ALPK1的作用机制涉及识别并特异性结合细菌脂多糖LPS合成的前体糖分子ADP-heptose(二磷酸腺苷庚糖),进而激活NF-κB通路介导的天然免疫炎症反应。ALPK1作为一种模式识别受体(PRR),在天然免疫反应中发挥重要作用,特别是在识别病原相关分子模式(PAMPs)和激活宿主免疫应答方面。ALPK1的激活可以诱导抗肿瘤免疫,在肿瘤免疫治疗领域具有潜在的应用价值。

热销产品

Recombinant Human Alpha-protein kinase 1 (ALPK1), partial (CSB-BP836286HU)

验证数据

CSB-BP836286HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ALPK1 Antibody (CSB-PA093012)

验证数据

CSB-PA093012

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/25.

CSB-PA093012

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/25.

ALPK1 Antibodies

ALPK1 for Homo sapiens (Human)

ALPK1 Proteins

ALPK1 Proteins for Homo sapiens (Human)