ADGRE1
ADGRE1，即粘附G蛋白偶联受体E1，别名EMR1、TM7LN3、F4/80等。它来源于人类基因编码，是G蛋白偶联受体2家族中的一员，特别是粘附G蛋白偶联受体（ADGR）亚家族的成员。在作用机制上，ADGRE1参与细胞黏附过程，并可能涉及免疫系统细胞间的相互作用。有研究表明，它还可能在调节性T细胞（Treg）的发育中发挥作用。ADGRE1与多种生物过程紧密相关。例如，在非洲家犬中，该基因受到强烈的正选择，与抵御疟原虫侵染的遗传机制有关。通过加强I型干扰素通路相关基因的表达量，ADGRE1能够抵抗疟原虫的侵染。ADGRE1在哺乳动物单核-巨噬细胞中也有表达，显示了其在免疫系统中的重要作用。
热销产品
ADGRE1 Antibody (CSB-PA613493ESR2HU)
验证数据
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA613493ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA 613493ESR2HU at dilution of 1:100
ADGRE1 Antibodies
ADGRE1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA007651GA01HU | EMR1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA613493ESR2HU | ADGRE1 Antibody | Human | ELISA, IHC |
| CSB-PA008040 | EMR1 Antibody | Human | WB, ELISA |
ADGRE1 Proteins
ADGRE1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP613493HU CSB-EP613493HU CSB-BP613493HU CSB-MP613493HU CSB-EP613493HU-B |
Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 1 (EMR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRE1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP719902RA CSB-EP719902RA CSB-BP719902RA CSB-MP719902RA CSB-EP719902RA-B |
Recombinant Rat EGF-like module-containing mucin-like hormone receptor-like 1 (Emr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRE1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP720253MO CSB-BP720253MO CSB-MP720253MO CSB-EP720253MO-B |
Recombinant Mouse Adhesion G protein-coupled receptor E1 (Adgre1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
