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ABCG2

ABCG2,即ATP结合盒亚家族G成员2,别名CD338、CDw338、MXR、MXR1。它是一种由ABCG2基因编码的跨膜转运蛋白,属于ATP结合盒(ABC)转运蛋白家族。ABCG2在多种组织中表达,包括肠道、胎盘、肝脏和肿瘤细胞。其作用机制是通过ATP水解提供能量,将多种底物,包括药物、代谢产物等从细胞内运输到细胞外,影响药物的吸收、分布和排泄。ABCG2参与调节细胞内外物质的平衡,对药物耐药性、细胞解毒、免疫调节和炎症反应等过程具有重要作用。ABCG2的异常表达或功能失调与多种疾病相关,包括肿瘤的多药耐药性、高尿酸血症和痛风等。

热销产品

Recombinant Human Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2), partial (CSB-YP891568HU1)

验证数据

CSB-YP891568HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ABCG2 Antibody (CSB-PA891568LA01HU)

验证数据

CSB-PA891568LA01HU

Immunofluorescent analysis of A549 cells using CSB-PA891568LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human ATP-binding cassette transporter G2,ABCG2 ELISA Kit (CSB-E11251h)

验证数据

CSB-E11251h 标准曲线

货号:CSB-E11251h

规格:96T/48T

灵敏度:0.039 ng/mL

检测范围:0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ABCG2 Antibodies

ABCG2 for Homo sapiens (Human)

ABCG2 Proteins

ABCG2 Proteins for Bos taurus (Bovine)

ABCG2 Proteins for Macaca mulatta (Rhesus macaque)

ABCG2 Proteins for Mus musculus (Mouse)

ABCG2 Proteins for Rattus norvegicus (Rat)

ABCG2 Proteins for Sus scrofa (Pig)

ABCG2 Proteins for Dictyostelium discoideum (Slime mold)

ABCG2 Proteins for Homo sapiens (Human)

ABCG2 ELISA Kit

ABCG2 ELISA Kit for Homo sapiens (Human)