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IL22RA1

IL22RA1,即白介素22受体α1,别名IL-22Rα1、CRF2-9等。它是一种由IL22RA1基因编码的蛋白质,是IL-22受体的α亚基,与IL-10Rβ链共用形成IL-22的高亲和力受体。IL22RA1的作用机制涉及与IL-22结合后,激活JAK/STAT信号通路,从而抑制IL-22介导的细胞增殖和抗凋亡。IL22RA1主要分布于胰、肝、小肠、结肠、肾等组织,参与调节上皮细胞的迁移能力、肝细胞的保护作用、呼吸道和胃肠道细胞的修复以及组织修复作用。此外,IL22RA1还参与了细菌防御、炎症性疾病的发生发展等过程,是相关疾病研究和治疗的潜在靶点。

热销产品

Recombinant Human Interleukin-22 receptor subunit alpha-1 (IL22RA1), partial (CSB-EP822717HU)

验证数据

CSB-EP822717HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

IL22RA1 Antibody (CSB-PA822717ESR2HU)

验证数据

CSB-PA822717ESR2HU

Western blot
All lanes: IL22RA1 antibody at 10μg/ml
Lane 1: Mouse spleen tissue
Lane 2: HepG2 whole cell lysate
Lane 3: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 63 kDa
Observed band size: 63 kDa

CSB-PA822717ESR2HU

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA822717ESR2HU at dilution of 1:100

CSB-PA822717ESR2HU

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA822717ESR2HU at dilution of 1:100

IL22RA1 Antibodies

IL22RA1 for Homo sapiens (Human)

IL22RA1 Proteins

IL22RA1 Proteins for Bos taurus (Bovine)

IL22RA1 Proteins for Mus musculus (Mouse)

IL22RA1 Proteins for Homo sapiens (Human)