Pig C-reactive protein,CRP ELISA Kit

文献引用 (2) 说明书下载

中文名称：

猪C反应蛋白(CRP)酶联免疫试剂盒
货号：

CSB-E08163p
规格：

96T/48T
价格：

￥4200/￥3000
其他：

CUSABIO Wins 2024 Bioz Rapid Star™ Award in the ELISA category

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猪C反应蛋白(CRP)酶联免疫试剂盒（CSB-E08163p）为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的CRP含量。C反应蛋白（CRP）是一种由肝脏在炎症反应中合成的急性期血清蛋白，能够与肺炎球菌的C多糖反应。CRP属于五聚体蛋白，主要功能包括促进细菌凝集、细菌荚膜肿胀、吞噬作用和补体固定。CRP作为炎症标志物，在细菌感染、炎症过程和组织损伤的监测中具有重要价值。试剂盒检测范围为0.625 ng/mL-40 ng/mL，该产品适用于动物模型研究、免疫调控机制探索或疫苗/药物疗效评价等科研场景，尤其可为猪类疾病的炎症相关研究（如感染性疾病模型构建、应激反应监测）提供可靠的数据支持本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：

CRP ELISA kit; PTX1C-reactive protein ELISA kit
缩写：

CRP
Uniprot No.：

O19062
种属：

Sus scrofa (Pig)
样本类型：

serum, plasma, tissue homogenates
检测范围：

0.625 ng/mL-40 ng/mL
灵敏度：

0.156 ng/mL
反应时间：

1-5h
样本体积：

50-100ul
检测波长：

450 nm
研究领域：

Immunology
测定原理：

quantitative
测定方法：

Sandwich
精密度：
线性度：
回收率：
标准曲线：
数据处理：

ELISA操作视频及标曲绘制软件下载
货期：

3-5 working days

引用文献

Dietary β-mannanase reduced post-weaning diarrhea of pigs by positively modulating gut microbiota and attenuating systemic immune responses KB Jang, Y Kim, J Ahn, JI Lee, S Park, J Choe, Y Kim,Animal Microbiome,2024
Mouse Model Infected Porcine Circovirus Types 2 Gang Liu et al,Journal of Animal and Veterinary Advances,2012

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功能：

Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
基因功能参考文献：
1. Enhanced external counterpulsation decreased C-reactive protein and increased flow-mediated dilation in hypercholesterolemia. PMID: 22681602
2. serum C-reactive protein correlates with macrophage accumulation and coronary artery disease in hypercholesterolemic pigs PMID: 12754176
3. CRP inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H oxidase via p38 kinase activation. PMID: 15718491
4. The present study shows that elevated levels of serum CRP and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS. (postweaning multisystemic wasting syndrome) PMID: 16817761
5. These data suggest that CRP might play a pathogenic role in the development of myointimal hyperplasia in polytetrafluoroethylene grafts. PMID: 17510097
6. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP PMID: 19036073
7. CRP stimulates superoxide production and the subsequent formation of peroxynitrite from basal released nitric oxide compromises PGI(2) synthesis. PMID: 19410579
8. Data show that during posttranplant obliterative bronchiolitis development, CRP is localized in inflammatory cells, myofibroblasts and endothelial cells probably as a part of the local inflammatory response. PMID: 19503785
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亚细胞定位：

Secreted.
蛋白家族：

Pentraxin family
组织特异性：

Found in plasma.
数据库链接：

KEGG: ssc:396842

STRING: 9823.ENSSSCP00000029570

UniGene: Ssc.16157

Pig C-reactive protein,CRP ELISA Kit

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