Recombinant Saccharomyces cerevisiae NADH-cytochrome b5 reductase 2 (MCR1)

in vitro E.coli expression system

中文名称：

酿酒酵母MCR1重组蛋白
货号：

CSB-CF006319SVG
规格：
来源：

in vitro E.coli expression system
其他：

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基因名：

MCR1
Uniprot No.：

P36060
别名：

MCR1; YKL150W; YKL605; NADH-cytochrome b5 reductase 2; Mitochondrial cytochrome b reductase; p34/p32
种属：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白长度：

Full Length of Mature Protein
表达区域：

42-302
氨基酸序列

ESNKVFKGDDKWIDLPISKIEEESHDTRRFTFKLPTEDSEMGLVLASALFAKFVTPKGSN VVRPYTPVSDLSQKGHFQLVVKHYEGGKMTSHLFGLKPNDTVSFKGPIMKWKWQPNQFKS ITLLGAGTGINPLYQLAHHIVENPNDKTKVNLLYGNKTPQDILLRKELDALKEKYPDKFN VTYFVDDKQDDQDFDGEISFISKDFIQEHVPGPKESTHLFVCGPPPFMNAYSGEKKSPKD QGELIGILNNLGYSKDQVFKF
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

N-terminal 10xHis-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

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功能：

The outer membrane form may mediate the reduction of outer membrane cytochrome b5, and the soluble inter-membrane space form may transfer electrons from external NADH to cytochrome c, thereby mediating an antimycin-insensitive, energy-coupled oxidation of external NADH by yeast mitochondria. Involved in the reduction of D-erythroascorbyl free radicals.
基因功能参考文献：
1. he high mcr-1 carriage rate in humans found in this study highlights the importance of continued vigilance, careful antibiotic stewardship, and the development of new antimicrobials. PMID: 29019312
2. The import pathways of the two MCR1 forms diverge in a stage before the encounter with the TOM complex and their mechanism of biogenesis represents a unique example how to achieve dual localization within one organelle. PMID: 18279676
亚细胞定位：

[NADH-cytochrome b5 reductase p32 form]: Mitochondrion intermembrane space.; [NADH-cytochrome b5 reductase p34 form]: Mitochondrion outer membrane; Single-pass membrane protein. Mitochondrion intermembrane space.
蛋白家族：

Flavoprotein pyridine nucleotide cytochrome reductase family
数据库链接：

KEGG: sce:YKL150W

STRING: 4932.YKL150W

Recombinant Saccharomyces cerevisiae NADH-cytochrome b5 reductase 2 (MCR1)

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