Recombinant Mouse Integral membrane protein 2A (Itm2a)-VLPs

中文名称：

小鼠Itm2a重组蛋白
货号：

CSB-MP011903MO
规格：
其他：

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基因名：

Itm2a
Uniprot No.：

Q61500
别名：

Itm2a; E25; Itm2; Integral membrane protein 2A; Protein E25
种属：

Mus musculus (Mouse)
来源：

Mammalian cell
表达区域：

1-263aa
氨基酸序列

MVKIAFNTPTAVQKEEARQDVEALVSRTVRAQILTGKELRVVPQEKDGSSGRCMLTLLGLSFILAGLIVGGACIYKYFMPKSTIYHGEMCFFDSEDPVNSIPGGEPYFLPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMTPKNLVELFGKLASGKYLPHTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

C-terminal 10xHis-tagged
If you have specified tag type, please tell us and we will check if it’s possible to develop.
产品提供形式：

Lyophilized powder
Note: We will default ship it in lyophilized form with normal bule ice packs. However, if you request to ship in liquid form, it needs to be shipped with dry ice, please communicate with us in advance and extra fees for dry ice and dry ice box will be charged.
缓冲液：

Lyophilized from PBS, 6% Trehalose, pH 7.4
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
注意事项：

Repeated freezing and thawing is not recommended. Store the protein at -20°C/-80°C upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity.
Datasheet & COA：

Please contact us to get it.

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基因功能参考文献：
1. Itm2a knockdown is sufficient to rescue the inhibitory effects of lamin A WT and R482W mutant overexpression on 3T3-L1 differentiation. PMID: 28872940
2. Itm2a possesses diverse functional properties as evidenced by differential expression during odontogenesis. PMID: 25079563
3. Itm2a is a target gene of GATA-3 that plays a minimal role in regulating the development and function of T cells PMID: 24831988
4. Itm2a is not only expressed in adult muscle fibres but also in the satellite cells responsible for regeneration. PMID: 23650549
5. Results support the involvement of Itm2a in the early stages of chondrogenesis in vitro. PMID: 15325075
6. Both Itm2a and Itm2c were not detected in the epididymis and vas deferens during sexual maturation. PMID: 17873332
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亚细胞定位：

Membrane; Single-pass type II membrane protein.
蛋白家族：

ITM2 family
组织特异性：

Expressed in mandibular condyles, in bone and in hair follicles. Strong expression in osteogenic tissues, such as neonatal calvaria, paws, tail and skin.
数据库链接：

KEGG: mmu:16431

STRING: 10090.ENSMUSP00000033591

UniGene: Mm.193

Recombinant Mouse Integral membrane protein 2A (Itm2a)-VLPs

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