Recombinant Human Membrane-spanning 4-domains subfamily A member 4A (MS4A4A)-VLPs

中文名称：

Recombinant Human Membrane-spanning 4-domains subfamily A member 4A (MS4A4A)-VLPs
货号：

CSB-MP822238HU
规格：

￥5250
图片：
The purity of VLPs was greater than 95% as determined by SEC-HPLC

CSB-MP822238HU is detected by Mouse anti-6*His monoclonal antibody.
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纯度：

Greater than 95% as determined by SEC-HPLC.
基因名：

MS4A4A
Uniprot No.：

Q96JQ5
别名：

CD20 antigen-like 1;Four-span transmembrane protein 1
种属：

Homo sapiens (Human)
蛋白长度：

Full Length
来源：

Mammalian cell
表达区域：

1-239aa
氨基酸序列

MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

C-terminal 10xHis-tagged
If you have specified tag type, please tell us and we will check if it's possible to develop.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

Lyophilized from PBS, 6% Trehalose, pH 7.4.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80℃. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
注意事项：

The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex. Repeated freezing and thawing is not recommended.Store the protein at -20℃/-80℃ upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).
Datasheet & COA：

Please contact us to get it.

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功能：

May be involved in signal transduction as a component of a multimeric receptor complex.
基因功能参考文献：
1. MS4A4A is expressed at the plasma membrane in monocytes but not in granulocytes or lymphocytes. PMID: 28303902
2. MS4A4A expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
3. MS4A4 in human mast cells effects ligand-induced KIT endocytosis pathways and reduced receptor recycling to the cell surface, thus promoting KIT signaling in the endosomes while reducing that in the plasma membrane. PMID: 25717186
4. Single nucleotide polymorphisms in APOE-epsilon4, CLU and MS4A4A influence both Alzheimer disease risk and cerebrospinal fluid Amyloid-beta1-42 levels. PMID: 23573206
亚细胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

MS4A family
组织特异性：

Variable expression in multiple hemopoietic cell lines.
数据库链接：

HGNC: 13371

OMIM: 606547

KEGG: hsa:51338

STRING: 9606.ENSP00000338648

UniGene: Hs.325960

Recombinant Human Membrane-spanning 4-domains subfamily A member 4A (MS4A4A)-VLPs

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