Recombinant Human Lipid phosphate phosphatase-related protein type 4 (LPPR4)

in vitro E.coli expression system

中文名称：

人PLPPR4重组蛋白
货号：

CSB-CF770341HU
规格：
来源：

in vitro E.coli expression system
其他：

产品详情
产品评价
相关产品
靶点详情

产品详情

基因名：

PLPPR4
Uniprot No.：

Q7Z2D5
别名：

PLPPR4; KIAA0455; LPPR4; PHP1; PRG1; Phospholipid phosphatase-related protein type 4; Brain-specific phosphatidic acid phosphatase-like protein 1; Lipid phosphate phosphatase-related protein type 4; Plasticity-related gene 1 protein; PRG-1
种属：

Homo sapiens (Human)
蛋白长度：

full length protein
表达区域：

1-763
氨基酸序列

MQRAGSSGGRGECDISGAGRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVI KDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAI PFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVG VHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTV INSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQ YKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSA KNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRA NTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMR SSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEET QENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGST VSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQT YELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSI SSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

N-terminal 10xHis-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

产品评价

靶点详情

功能：

Postsynaptic density membrane protein that indirectly regulates glutamatergic synaptic transmission through lysophosphatidic acid (LPA)-mediated signaling pathways. Binds lysophosphatidic acid (LPA) and mediates its internalization into cells. Could act as receptor or a transporter of this lipid at the post-synaptic membrane. Modulates lysophosphatidic acid (LPA) activity in neuron axonal outgrowth during development by attenuating phospholipid-induced axon collapse.
基因功能参考文献：
1. Glycosylation as a critical mechanism for PRG-1 function was significantly reduced by the PRG-1R346T SNP glycosylation as a critical mechanism PMID: 26671989
亚细胞定位：

Cell junction, synapse, postsynaptic density membrane; Multi-pass membrane protein.
蛋白家族：

PA-phosphatase related phosphoesterase family
组织特异性：

Expressed by glutamatergic neurons (at protein level).
数据库链接：

HGNC: 23496

OMIM: 607813

KEGG: hsa:9890

STRING: 9606.ENSP00000359204

UniGene: Hs.13245

Recombinant Human Lipid phosphate phosphatase-related protein type 4 (LPPR4)

产品详情

产品评价

相关产品

靶点详情

Most popular with customers

产品中心

信号通路

技术信息

联系信息