Recombinant Bovine Cation-dependent mannose-6-phosphate receptor (M6PR)-VLPs

中文名称：

牛M6PR重组蛋白
货号：

CSB-MP013293BO
规格：
其他：

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基因名：

M6PR
Uniprot No.：

P11456
别名：

M6PR; Cation-dependent mannose-6-phosphate receptor; CD Man-6-P receptor; CD-MPR; 46 kDa mannose 6-phosphate receptor; MPR 46
种属：

Bos taurus (Bovine)
来源：

Mammalian cell
表达区域：

29-279aa
氨基酸序列

TEEKTCDLVGEKGKESEKELALLKRLTPLFNKSFESTVGQSPDMYSYVFRVCREAGNHSSGAGLVQINKSNGKETVVGRFNETQIFNGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTLASLVAVYIIGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

C-terminal 10xHis-tagged
If you have specified tag type, please tell us and we will check if it’s possible to develop.
产品提供形式：

Lyophilized powder
Note: We will default ship it in lyophilized form with normal bule ice packs. However, if you request to ship in liquid form, it needs to be shipped with dry ice, please communicate with us in advance and extra fees for dry ice and dry ice box will be charged.
缓冲液：

Lyophilized from PBS, 6% Trehalose, pH 7.4
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
注意事项：

Repeated freezing and thawing is not recommended. Store the protein at -20°C/-80°C upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity.
Datasheet & COA：

Please contact us to get it.

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功能：

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
基因功能参考文献：
1. Rotaviruses reach late endosomes and require M6PR and cathepsin proteases to enter the cell. PMID: 24501398
2. Expression and binding properties of mannose-6-phosphate receptors CD-MPR and CI-MPR differ during perinatal development in rat liver. PMID: 12127995
亚细胞定位：

Lysosome membrane; Single-pass type I membrane protein.
数据库链接：

KEGG: bta:281291

STRING: 9913.ENSBTAP00000024233

UniGene: Bt.5032

Recombinant Bovine Cation-dependent mannose-6-phosphate receptor (M6PR)-VLPs

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