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  4. Recombinant Xenopus laevis Transforming acidic coiled-coil-containing protein 3 (tacc3), partial

Recombinant Xenopus laevis Transforming acidic coiled-coil-containing protein 3 (tacc3), partial

  • 中文名称：
    有爪蟾蜍tacc3重组蛋白
  • 货号：
    CSB-YP868695XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    有爪蟾蜍tacc3重组蛋白
  • 货号：
    CSB-EP868695XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    有爪蟾蜍tacc3重组蛋白
  • 货号：
    CSB-EP868695XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    有爪蟾蜍tacc3重组蛋白
  • 货号：
    CSB-BP868695XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    有爪蟾蜍tacc3重组蛋白
  • 货号：
    CSB-MP868695XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    tacc3
  • Uniprot No.：
    Q9PTG8
  • 别名：
    tacc3; maskin; Transforming acidic coiled-coil-containing protein 3; Cytoplasmic polyadenylation element-binding protein-associated factor Maskin; CPEB-associated factor Maskin
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Maternal RNA in oocytes remains in a dormant state as masking outcompetes eif4g to bind eif4e, thereby preventing translation. During oocyte maturation this complex dissolves and eif4g binds eif4e to allow translation of maternal RNAs. Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in microtubule assembly during M-phase. Involved in spindle pole assembly by recruiting and regulating ckap5 at the spindle pole leading to microtubule elongation.
  • 基因功能参考文献：
    1. TACC1 and TACC3 are each required for maintaining normal microtubule growth speed in Xenopus PMID: 26012630
    2. XTACC3 can induce the recruitment of larger amounts of XMAP215 by increasing its local concentration, thereby promoting efficient microtubule elongation during mitosis PMID: 25262927
    3. TACC3 promotes axon outgrowth and regulates microtubule dynamics in multiple embryonic cell types. PMID: 25187649
    4. Maskin functions in mitotic spindle assembly. PMID: 15788567
    5. Maskin activity and localization is controlled by differential phosphorylation PMID: 16107707
    6. Maskin phosphorylation-dephosphorylation also oscillates with the cell cycle and is controlled by the kinase CDK1 and the phosphatase calcineurin PMID: 17086181
    7. Maskin mRNA is translationally regulated by at least two repressor elements and an activation element. PMID: 17241108

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  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族：
    TACC family
  • 数据库链接：

    KEGG: xla:398145

    UniGene: Xl.25749

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