Recombinant Saccharomyces cerevisiae THO complex subunit 2 (THO2), partial

中文名称：

酿酒酵母THO2重组蛋白
货号：

CSB-YP023502SVG
规格：
来源：

Yeast
其他：

中文名称：

酿酒酵母THO2重组蛋白
货号：

CSB-EP023502SVG
规格：
来源：

E.coli
其他：

中文名称：

酿酒酵母THO2重组蛋白
货号：

CSB-EP023502SVG-B
规格：
来源：

E.coli
共轭：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名称：

酿酒酵母THO2重组蛋白
货号：

CSB-BP023502SVG
规格：
来源：

Baculovirus
其他：

中文名称：

酿酒酵母THO2重组蛋白
货号：

CSB-MP023502SVG
规格：
来源：

Mammalian cell
其他：

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纯度：

>85% (SDS-PAGE)
基因名：

THO2
Uniprot No.：

P53552
别名：

THO2; LDB5; RLR1; ZRG13; YNL139C; N1209; N1835; THO complex subunit 2; Low dye-binding protein 5; THO complex subunit RLR1; Zinc-regulated gene 13 protein
种属：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白长度：

Partial
蛋白标签：

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
产品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

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功能：

Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase. It functions in cotranscriptional formation of an export-competent messenger ribonucleoprotein particle (mRNP) by facilitating the loading of ATP-dependent RNA helicase SUB2 and the mRNA export factor YRA1 along the nascent mRNA.
基因功能参考文献：
1. THO2 mutants show defective meiosis and an impairment of premeiotic replication as well as DNA-damage accumulation. PMID: 22878416
亚细胞定位：

Nucleus.
蛋白家族：

THOC2 family
数据库链接：

KEGG: sce:YNL139C

STRING: 4932.YNL139C

Recombinant Saccharomyces cerevisiae THO complex subunit 2 (THO2), partial

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