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  4. Recombinant Saccharomyces cerevisiae Phosphatidylinositol 4-kinase PIK1 (PIK1), partial

Recombinant Saccharomyces cerevisiae Phosphatidylinositol 4-kinase PIK1 (PIK1), partial

  • 中文名称：
    酿酒酵母PIK1重组蛋白
  • 货号：
    CSB-YP327934SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    酿酒酵母PIK1重组蛋白
  • 货号：
    CSB-EP327934SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    酿酒酵母PIK1重组蛋白
  • 货号：
    CSB-EP327934SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    酿酒酵母PIK1重组蛋白
  • 货号：
    CSB-BP327934SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    酿酒酵母PIK1重组蛋白
  • 货号：
    CSB-MP327934SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PIK1
  • Uniprot No.：
    P39104
  • 别名：
    PIK1; YNL267W; N0795; Phosphatidylinositol 4-kinase PIK1; PI4-kinase; PtdIns-4-kinase; EC 2.7.1.67
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,-trisphosphate. PIK1 is part of a nuclear phosphoinositide cycle and could control cytokinesis through the actin cytoskeleton.
  • 基因功能参考文献：
    1. Inhibition of Gga2-Pik1 binding resulted in reduced Pik1 localization and delayed accumulation of phosphatidylinositol 4-phosphate to the trans-Golgi network. PMID: 28289207
    2. Thus, our results suggest that pik1(+) is required for the maintenance of circular chromosomes. PMID: 29410177
    3. Data show that Gga2p binds directly to the Gga2p binds directly to the trans-Golgi network (TGN) PtdIns(4)-kinase Pik1p and contributes to Pik1p recruitment. PMID: 22344030
    4. Catalytically inactive derivatives of these compartment-restricted Pik1 constructs indicated that PtdIns4P must be generated both in the nucleus and at the Golgi for normal cell function. PMID: 16365163
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    PI3/PI4-kinase family, Type III PI4K subfamily
  • 数据库链接：

    KEGG: sce:YNL267W

    STRING: 4932.YNL267W

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